Title:
Assembly of Big Genomic Data
Assembly of Big Genomic Data
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Author(s)
Medvedev, Paul
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Abstract
As genome sequencing technologies continue to facilitate the generation of large datasets, developing
scalable algorithms has come to the forefront as a crucial step in analyzing these datasets. In this talk,
I will discuss several recent advances, with a focus on the problem of reconstructing a genome from a
set of reads (genome assembly). I will describe low-memory and scalable algorithms for automatic
parameter selection and de Bruijn graph compaction, recently implemented in two tools: KmerGenie
and bcalm. I will also present recent advances in the theoretical foundations of genome assemblers.
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Date Issued
2017-09-15
Extent
57:58 minutes
Resource Type
Moving Image
Resource Subtype
Lecture