Title:
Poly(para-phenyleneethynylene)s: probing the biological interface with biomolecular materials

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dc.contributor.advisor Bunz, Uwe H. F.
dc.contributor.author Phillips, Ronald Lee, III en_US
dc.contributor.committeeMember Andrew Lyon
dc.contributor.committeeMember Laren Tolbert
dc.contributor.committeeMember Nicholas Hud
dc.contributor.committeeMember Sherry Michele Owen
dc.contributor.department Chemistry and Biochemistry en_US
dc.date.accessioned 2009-01-22T15:45:30Z
dc.date.available 2009-01-22T15:45:30Z
dc.date.issued 2008-08-20 en_US
dc.description.abstract The synthesis and biological sensing applications of novel water soluble poly(para-phenyleneethynylene)s (PPEs) are presented. The ease of synthesis, synthetic variability, and dramatic chromicity of PPEs makes them well suited for biological and sensing applications. Molecular recognition and signal transduction can be achieved by using PPEs as sensory materials. By incorporating biological functional groups (e.g. sugars), PPEs can efficiently detect the presence of toxic heavy metals, proteins, and bacteria through either fluorescence quenching or enhancement. Rapid, precise, and convenient sensory arrays for the detection of biological analytes are possible through the formation of gold nanoparticle-PPE constructs. en_US
dc.description.degree Ph.D. en_US
dc.identifier.uri http://hdl.handle.net/1853/26555
dc.publisher Georgia Institute of Technology en_US
dc.subject Polymer en_US
dc.subject Biosensor en_US
dc.subject Nanoparticle en_US
dc.subject Fluorescence en_US
dc.subject Bacteria en_US
dc.subject Assays en_US
dc.subject.lcsh Biological interfaces
dc.subject.lcsh Biomolecules
dc.subject.lcsh Biosensors
dc.subject.lcsh Chemical detectors
dc.subject.lcsh Conjugated polymers
dc.title Poly(para-phenyleneethynylene)s: probing the biological interface with biomolecular materials en_US
dc.type Text
dc.type.genre Dissertation
dspace.entity.type Publication
local.contributor.corporatename School of Chemistry and Biochemistry
local.contributor.corporatename College of Sciences
relation.isOrgUnitOfPublication f1725b93-3ab8-4c47-a4c3-3596c03d6f1e
relation.isOrgUnitOfPublication 85042be6-2d68-4e07-b384-e1f908fae48a
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