Title:
Emergence of Genetic Complexity in Clonal Populations Evolving in the Lab: Implications for Cancer and Chronic Infectious Disease
Emergence of Genetic Complexity in Clonal Populations Evolving in the Lab: Implications for Cancer and Chronic Infectious Disease
| dc.contributor.author | Rosenzweig, Frank | |
| dc.contributor.corporatename | Georgia Institute of Technology. Institute for Bioengineering and Bioscience | en_US |
| dc.contributor.corporatename | Georgia Institute of Technology. School of Biological Sciences | en_US |
| dc.date.accessioned | 2018-10-26T20:14:16Z | |
| dc.date.available | 2018-10-26T20:14:16Z | |
| dc.date.issued | 2018-10-09 | |
| dc.description | Presented on October 9, 2018 from 8:30 a.m.-9:30 a.m. at the Parker H. Petit Institute for Bioengineering and Bioscience (IBB), Room 1128, Georgia Tech. | en_US |
| dc.description | Frank Rosenzweig is a Professor in the School of Biological Sciences, Georgia Tech. | en_US |
| dc.description | Runtime: 73:00 minutes | en_US |
| dc.description.abstract | A bacterial population that initially consists of a single clone can evolve into a population teeming with many, whether or not the surrounding environment is structured, and whether or not resource levels are constant or fluctuating. Emergence of genetic complexity, measured as functional information, has been variously attributed to balancing selection, clonal interference and/or clonal reinforcement arising from either antagonistic or synergistic interactions among evolving lineages. Using a combination of theory and experiment, we seek to define the boundary conditions under which one causal mechanism prevails over another. These investigations illuminate the process of adaptive evolution in other populations that originate as a single clone: those that give rise to cancer and those that bring about chronic infectious disease. | en_US |
| dc.format.extent | 73:00 minutes | |
| dc.identifier.uri | http://hdl.handle.net/1853/60499 | |
| dc.language.iso | en_US | en_US |
| dc.publisher | Georgia Institute of Technology | en_US |
| dc.relation.ispartofseries | Petit Institute Breakfast Club Seminar Series | |
| dc.subject | Clonal interference and reinforcement | en_US |
| dc.title | Emergence of Genetic Complexity in Clonal Populations Evolving in the Lab: Implications for Cancer and Chronic Infectious Disease | en_US |
| dc.title.alternative | Emergence of Genetic Complexity in Clonal Populations Evolving in the Lab: Implications for Cancer and Chronic Infections | en_US |
| dc.type | Moving Image | |
| dc.type.genre | Lecture | |
| dspace.entity.type | Publication | |
| local.contributor.author | Rosenzweig, Frank | |
| local.contributor.corporatename | Parker H. Petit Institute for Bioengineering and Bioscience | |
| local.relation.ispartofseries | Petit Institute Breakfast Club Seminar Series | |
| relation.isAuthorOfPublication | 3ad66290-a3ab-4897-954a-d8ec6198b82e | |
| relation.isOrgUnitOfPublication | d978f252-ad5a-4fe6-a735-21050b2d760e | |
| relation.isSeriesOfPublication | 037a6ee9-c6f0-4f20-abb8-e229d98f6754 |
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