Title:
Segmenting Images Analytically in Shape Space

dc.contributor.author Rathi, Yogesh
dc.contributor.author Dambreville, Samuel
dc.contributor.author Niethammer, Marc
dc.contributor.author Malcolm, James G.
dc.contributor.author Levitt, James
dc.contributor.author Tannenbaum, Allen R.
dc.contributor.corporatename Georgia Institute of Technology. Dept. of Biomedical Engineering
dc.contributor.corporatename Emory University. Dept. of Biomedical Engineering
dc.contributor.corporatename Georgia Institute of Technology. School of Electrical and Computer Engineering
dc.contributor.corporatename Brigham and Women’s Hospital
dc.contributor.corporatename Harvard Medical School
dc.date.accessioned 2009-06-22T20:28:47Z
dc.date.available 2009-06-22T20:28:47Z
dc.date.issued 2008-02
dc.description ©2008 SPIE--The International Society for Optical Engineering. One print or electronic copy may be made for personal use only. Systematic reproduction and distribution, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper are prohibited. The electronic version of this article is the complete one and can be found online at: http://dx.doi.org/10.1117/12.769511 en
dc.description Presented at Medical Imaging 2008: Image Processing, February 17-19, 2008, San Diego, CA, USA.
dc.description DOI: 10.1117/12.769511
dc.description.abstract This paper presents a novel analytic technique to perform shape-driven segmentation. In our approach, shapes are represented using binary maps, and linear PCA is utilized to provide shape priors for segmentation. Intensity based probability distributions are then employed to convert a given test volume into a binary map representation, and a novel energy functional is proposed whose minimum can be analytically computed to obtain the desired segmentation in the shape space. We compare the proposed method with the log-likelihood based energy to elucidate some key differences. Our algorithm is applied to the segmentation of brain caudate nucleus and hippocampus from MRI data, which is of interest in the study of schizophrenia and Alzheimer's disease. Our validation (we compute the Hausdorff distance and the DICE coefficient between the automatic segmentation and ground-truth) shows that the proposed algorithm is very fast, requires no initialization and outperforms the log-likelihood based energy. en
dc.identifier.citation Yogesh Rathi, Samuel Dambreville, Marc Niethammer, James Malcolm, James Levitt, Martha E. Shenton, and Allen Tannenbaum, "Segmenting images analytically in shape space," Medical Imaging 2008: Image Processing, Joseph M. Reinhardt, Josien P. W. Pluim, Editors, Proc. SPIE, Vol. 6914, 691405 (2008) en
dc.identifier.issn 0277-786X
dc.identifier.uri http://hdl.handle.net/1853/28594
dc.language.iso en_US en
dc.publisher Georgia Institute of Technology en
dc.publisher.original Society of Photo-Optical Instrumentation Engineers
dc.subject Algorithms
dc.subject Shape-driven segmentation
dc.subject Principal component analysis
dc.subject Automatic segmentation algorithms
dc.subject Image segmentation
dc.title Segmenting Images Analytically in Shape Space en
dc.type Text
dc.type.genre Proceedings
dspace.entity.type Publication
local.contributor.corporatename Wallace H. Coulter Department of Biomedical Engineering
relation.isOrgUnitOfPublication da59be3c-3d0a-41da-91b9-ebe2ecc83b66
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