Title:
Environmental Fate and Transport of Veterinary Antibiotics
Environmental Fate and Transport of Veterinary Antibiotics
Author(s)
Callura, Jonathan Charles
Advisor(s)
Huang, Dr. Ching-Hua
Editor(s)
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Abstract
Veterinary antibiotics such as ionophores and tetracyclines are commonly used in farming operations to prevent disease and promote growth
rates in poultry, cattle, and swine. Since waste products from treated animals are used as fertilizers, there is a growing concern that these
compounds may leach into the soil and water supply causing chronic low-level exposure to humans and leading to the development of antibiotic-
resistant bacteria. Due to close structural similarities and physical properties, nigericin was determined to be an effective surrogate
standard for the detection of the monensin, salinomycin, and narasin. Aluminum sulfate addition was considered as a potential treatment
method to reduce antibiotic mobility, which resulted in an approximately 80% reduction of recovery rates for tetracyclines in poultry litter
samples. Strong anion exchange cartridges were used in tandem with standard hydrophilic-lipophilic balanced cartridges which resulted in
more rapid extractions and faster sample processing. Demeclocycline exhibited the potential to be used as a surrogate standard for tetracyclines
due to close similarities in detection levels. This study has developed a method for detecting antibiotics in several types of environmental
media and reinforced potential treatment methods as a means to reduce the risk of exposure to microcontaminants in the water supply.
Sponsor
Office of Student Media; Undergraduate Research Opportunities Program; Georgia Tech Library.
Date Issued
2013
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Article