Title:
Flow Patterns and Wall Shear Stress Distributions at Atherosclerotic-Prone Sites in a Human Left Coronary Artery - An Exploration Using Combined Methods of CT and Computational Fluid Dynamics

dc.contributor.author Jin, Suo
dc.contributor.author Yang, Yan
dc.contributor.author Oshinski, John N.
dc.contributor.author Tannenbaum, Allen R.
dc.contributor.author Gruden, James
dc.contributor.author Giddens, Don P.
dc.contributor.corporatename Georgia Institute of Technology. Dept. of Biomedical Engineering
dc.contributor.corporatename Emory University. Dept. of Biomedical Engineering
dc.contributor.corporatename Emory University. Dept. of Radiology
dc.date.accessioned 2009-11-16T18:11:17Z
dc.date.available 2009-11-16T18:11:17Z
dc.date.issued 2004-09
dc.description ©2004 IEEE. Personal use of this material is permitted. However, permission to reprint/republish this material for advertising or promotional purposes or for creating new collective works for resale or distribution to servers or lists, or to reuse any copyrighted component of this work in other works must be obtained from the IEEE. This material is presented to ensure timely dissemination of scholarly and technical work. Copyright and all rights therein are retained by authors or by other copyright holders. All persons copying this information are expected to adhere to the terms and constraints invoked by each author's copyright. In most cases, these works may not be reposted without the explicit permission of the copyright holder. en
dc.description.abstract Computed tomography (CT) slices are combined with computational fluid dynamics (CFD) to simulate the flow patterns in a human left coronary artery. The vascular model was reconstructed from CT slices scanned from a healthy volunteer in vivo. The spatial resolution of the slices is 0.6 × 0.6 × 0.625 mm so that geometrical details of the local wall surface of the vessel could be considered in the CFD modeling. This level of resolution is needed to investigate the wall shear stress (WSS) distribution, a factor generally recognized as a related to the atherogenesis. The WSS distributions on the main trunk and bifurcation of the left coronary artery of the model in one cardiac cycle are presented, and the results demonstrate that low and oscillating WSS is correlative with clinical observations of the atherosclerotic-prone sites in the left coronary artery. en
dc.identifier.citation Suo Jin, Yan Yang, John Oshinski, Allen Tannenbaum, James Gruden and Don Giddens, "Flow Patterns and Wall Shear Stress Distributions at Atherosclerotic-Prone Sites in a Human Left Coronary Artery - An Exploration Using Combined Methods of CT and Computational Fluid Dynamics," 26th Annual International Conference of the IEEE Engineering in Medicine and Biology Society : conference proceedings : linkages for innovation in biomedicine, 2004, Vol. 2, 3789- 3791. en
dc.identifier.isbn 0-7803-8439-3
dc.identifier.uri http://hdl.handle.net/1853/31210
dc.language.iso en_US en
dc.publisher Georgia Institute of Technology en
dc.publisher.original Institute of Electrical and Electronics Engineers
dc.subject Computational fluid dynamics en
dc.subject Computed tomography en
dc.subject Wall shear stress en
dc.subject Coronary artery en
dc.title Flow Patterns and Wall Shear Stress Distributions at Atherosclerotic-Prone Sites in a Human Left Coronary Artery - An Exploration Using Combined Methods of CT and Computational Fluid Dynamics en
dc.type Text
dc.type.genre Proceedings
dspace.entity.type Publication
local.contributor.author Oshinski, John N.
local.contributor.corporatename Wallace H. Coulter Department of Biomedical Engineering
relation.isAuthorOfPublication 05472fe1-6d57-4489-af83-42115a3f55cc
relation.isOrgUnitOfPublication da59be3c-3d0a-41da-91b9-ebe2ecc83b66
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