BOLD Signal Changes in Resting State Networks are Related to Performance on a Vigilance Task

Merritt, Mac

Title:

BOLD Signal Changes in Resting State Networks are Related to Performance on a Vigilance Task

dc.contributor.advisor	Keilholz, Dr. Shella
dc.contributor.author	Merritt, Mac
dc.date.accessioned	2013-06-18T18:02:35Z
dc.date.available	2013-06-18T18:02:35Z
dc.date.issued	2013
dc.description	The Tower is an official publication of the Georgia Tech Office of Student Media and is sponsored by the Undergraduate Research Opportunities Program and the Georgia Tech Library. This article appeared in Volume 5, pages 51-54.	en_US
dc.description.abstract	Purpose and Background: Recent research has shown that spatially separated brain regions often display functional synchrony that relates to brain state and human performance. Two important anti-correlated functional networks that are seen with resting state functional magnetic resonance imaging (fMRI) are the default mode network (DMN) and the task positive network (TPN). Analytically defining these two networks to better understand their behavior may have a critical impact on understanding higher level function and human performance. Methods: 17 participants were scanned using fMRI in two different states: while performing the psychomotor vigilance task (PVT) and while in resting state. Using seed based correlation defined networks, the behavior of the TPN and DMN were tested for dynamic behavior after the onset of the task and the shifts in the magnitude of the signal in each network was compared to reaction time on the PVT using a linear regression. Results and conclusion: The signal in each network changed significantly in response to the task (TPN increased with a peak at 6 seconds, DMN decreased with a peak at 12 seconds). The magnitude of the increase in the signal within the TPN was significantly related to response time on the PVT. This study validates a network generation technique that can be used in future studies to further investigate the behavior of functional networks, and it shows a relationship between shifts within the TPN and behavior on this vigilance task.	en_US
dc.description.sponsorship	Office of Student Media; Undergraduate Research Opportunities Program; Georgia Tech Library.	en_US
dc.embargo.terms	null	en_US
dc.identifier.uri	http://hdl.handle.net/1853/47813
dc.language.iso	en	en_US
dc.publisher	Georgia Institute of Technology	en_US
dc.relation.ispartofseries	The Tower. Volume 5, Spring 2013	en_US
dc.title	BOLD Signal Changes in Resting State Networks are Related to Performance on a Vigilance Task	en_US
dc.type	Text
dc.type.genre	Article
dspace.entity.type	Publication
local.contributor.corporatename	Undergraduate Research Opportunities Program
relation.isOrgUnitOfPublication	0db885f5-939b-4de1-807b-f2ec73714200