Title:
Quantification of Microvessel Fragments from Primary Isolation Using 3-D Confocal Microscopy
Quantification of Microvessel Fragments from Primary Isolation Using 3-D Confocal Microscopy
| dc.contributor.advisor | Guldberg, Robert | |
| dc.contributor.author | Rather, Matthew Holt | |
| dc.contributor.department | Biomedical Engineering (Joint GT/Emory Department) | |
| dc.date.accessioned | 2018-08-20T19:10:42Z | |
| dc.date.available | 2018-08-20T19:10:42Z | |
| dc.date.created | 2017-12 | |
| dc.date.issued | 2017-12 | |
| dc.date.submitted | December 2017 | |
| dc.date.updated | 2018-08-20T19:10:42Z | |
| dc.description.abstract | Angiogenesis, or the migration, growth, and differentiation of endothelial cells to form new blood vessels, is an essential component in any tissue engineering project. A variety of studies with transgenic and gene-targeted mice have demonstrated the importance of angiogenesis in fracture healing, and have provided insights into regulatory processes governing fracture angiogenesis; however, patterns of microvessel development before implementation and their effect on bone growth have yet to be quantified. Here we search to find the best quantification parameters of microvessels through 3-D confocal microscopy as they grow in-vitro before being seeded in a scaffold and delivered to a bone defect. Quantification will be done through both Amira and ImageJ software as each program has its strengths and weaknesses in image quantification. | |
| dc.description.degree | Undergraduate | |
| dc.format.mimetype | application/pdf | |
| dc.identifier.uri | http://hdl.handle.net/1853/60348 | |
| dc.language.iso | en_US | |
| dc.publisher | Georgia Institute of Technology | |
| dc.subject | Angiogenesis | |
| dc.subject | Tissue Engineering | |
| dc.subject | Confocal Microscopy | |
| dc.subject | Imaging | |
| dc.title | Quantification of Microvessel Fragments from Primary Isolation Using 3-D Confocal Microscopy | |
| dc.type | Text | |
| dc.type.genre | Undergraduate Thesis | |
| dspace.entity.type | Publication | |
| local.contributor.corporatename | Wallace H. Coulter Department of Biomedical Engineering | |
| local.contributor.corporatename | Undergraduate Research Opportunities Program | |
| local.contributor.corporatename | College of Engineering | |
| local.relation.ispartofseries | Undergraduate Research Option Theses | |
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| relation.isSeriesOfPublication | e1a827bd-cf25-4b83-ba24-70848b7036ac | |
| thesis.degree.level | Undergraduate |