Title:
Engineering a cellulolytic escherichia coli towards consolidated bioprocessing

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dc.contributor.advisor Chen, Rachel
dc.contributor.author Sekar, Ramanan en_US
dc.contributor.committeeMember Banerjee, Sujit
dc.contributor.committeeMember Stycznski, Mark
dc.contributor.department Chemical Engineering en_US
dc.date.accessioned 2013-01-17T21:52:15Z
dc.date.available 2013-01-17T21:52:15Z
dc.date.issued 2011-11-07 en_US
dc.description.abstract The current energy crisis is exponentially growing and widening the chasm between demand and supply. Biofuels such as ethanol not only provide greener alternatives to fossil fuels but have been shown to reduce emissions from vehicles, improving air etc. Biofuel production from sources such as cellulose is believed to be more sustainable due to its low cost, vast availability in nature and sources such as industrial plant waste can be put to good use. However, due to the absence of a low-cost technology to overcome its recalcitrance, a concept called Consolidated Bioprocessing (CBP) has been put forward which proposes to integrate the production of saccharolytic enzymes, hydrolysis of the carbohydrate components to sugar molecules, and the fermentation of hexose and pentose sugars to biofuels into a single process. The present study involves development of cellulolytic E. coli strains towards cellodextrin assimilation by employing an energy-saving strategy in cellulose metabolism through the phosphorolytic cleavage of cellodextrin mixture produced as cellulosic degradation products. en_US
dc.description.degree MS en_US
dc.identifier.uri http://hdl.handle.net/1853/45875
dc.publisher Georgia Institute of Technology en_US
dc.subject Saccharophagus degradans en_US
dc.subject Lactose permease en_US
dc.subject Bioethanol en_US
dc.subject Phosphorylase en_US
dc.subject.lcsh Biomass energy
dc.subject.lcsh Cellulosic ethanol
dc.subject.lcsh Ethanol
dc.subject.lcsh Enzymes
dc.subject.lcsh Lignocellulose
dc.subject.lcsh Waste products as fuel
dc.title Engineering a cellulolytic escherichia coli towards consolidated bioprocessing en_US
dc.type Text
dc.type.genre Thesis
dspace.entity.type Publication
local.contributor.corporatename School of Chemical and Biomolecular Engineering
local.contributor.corporatename College of Engineering
relation.isOrgUnitOfPublication 6cfa2dc6-c5bf-4f6b-99a2-57105d8f7a6f
relation.isOrgUnitOfPublication 7c022d60-21d5-497c-b552-95e489a06569
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