Person:
Brand, Oliver

Permanent Link
https://hdl.handle.net/1853/71115
Associated Organization(s)
ORCID
ArchiveSpace Name Record

Filters
2008 1
1
1
1
1
Reset filters

Settings
Author: Brand, Oliver × End date: 2009 × Start date: 2003 × search.filters.applied.f.isSeriesOfPublicationTitle: NanoFANS Forum ×

Publication Search Results

Now showing 1 - 1 of 1
  • No Thumbnail Available
    Item
    Mass-Sensitive Biochemical Microsensors
    (Georgia Institute of Technology, 2008-10-10) Brand, Oliver
    A resonant microsensor platform based on disk-type microstructures vibrating in an in-plane resonance mode for chemical and biochemical sensing applications in gas and liquid environments is presented. Based on measured short-term frequency stabilities of 1.1 10^-8 in air and 2.3 10^-6 in water, mass detection limits in the low femtogram and sub-picogram, respectively, are achieved. In a biosensing application, biomolecules are immobilized on the resonator surface. Upon selective binding of analyte molecules (e.g. via antibody-antigen binding), the mass of the resonator is increased, resulting in a measurable decrease of its resonance frequency. The feasibility of liquid-phase biosensing using the disk resonators is demonstrated experimentally by detecting anti-beta-galactosidase antibody using covalently immobilized beta-galactosidase enzyme.