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Publication Search Results

Now showing 1 - 10 of 269
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Green and effective continuous multi-step synthesis of ring-fused heteroaromatics

2013 , Liotta, Charles L. , Eckert, Charles A. , France, Stefan , Pollet, Pamela

Historically, batch processing has been the major strategy in the synthesis of complex molecules, especially molecules of pharmaceutical interest. In general, this approach has been fraught with high cost, excessive time for scale-up, and waste issues. In order to address these issues, continuous flow technology has been identified as an alternative production vehicle since it has both environmental and economic advantages. Continuous flow technology offers superior mass and heat transfer, and lower production costs when compared with the traditional batch technology. Technological transfer from batch to continuous flow maximizes performance in terms of product yield and selectivity while minimizing solvent and catalyst needs thereby lowering production costs. In addition, continuous flow processes can be “scaled out” in contrast to batch processes that must be “scaled up.” In this research project, we take advantage of continuous flow technology to conduct the multi-step synthesis shown in Scheme 1.

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Design of advanced sensing materials

2011-05-29 , Janata, Jiří , Josowicz, Miroslawa

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Conference support for the 9th international symposium on functional π-electron systems

2011-02-28 , Marder, Seth R.

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Theoretical models for potential energy landscapes of challenging chemical systems

2010-12-31 , Sherrill, C. David

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Black to transmissive electrochromatic windows

2012-12 , Reynolds, John R. , Dyer, Aubrey L.

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Product imaging of photodissociations and reactions of atmospherically important molecules

2011-03-31 , Houston, Paul L.

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Cruciforms: development of a responsive fluorophore

2011-01-31 , Bunz, Uwe H. F.

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Intercalation mediated assembly and the first informational polymers of life

2012-05-04 , Hud, Nicholas V.

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REU site: research experiences for undergraduates in chemistry and biochemistry

2011-03-14 , Collard, David M. , Tyson, J. Cameron

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Design, fabrication, and testing of microDSC sensors

2011-01-15 , Bottomley, Lawrence A.