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ItemPRedicting Emergence Of Virulent Entities By Novel Technologies (PREVENT) Symposium - Session 1, End-to-End Theme(Georgia Institute of Technology, 2021-02-22) Marathe, Madhav ; Peters, Debra ; Ke, RuianMadhav Marathe - Plenary Talk TITLE: "Real-time End-to-End Pandemic Planning, Prediction and Response". The COVID-19 pandemic has brought forth the need for a sustainable capability for pandemic planning, response, and mitigation at various geographic, temporal and social scales. The social, economic, and health impact of the pandemic has been immense and will continue to be felt for decades to come. Since February 2020, our group has been providing local, state, and federal authorities continuous modeling and analytics support as they work assiduously to contain the pandemic. Based on this experience, I will describe the scientific and engineering challenges and opportunities in developing an end-to-end program to better prepare and respond to future pandemics and epidemic outbreaks.