(Georgia Institute of Technology, 2011-01-27)
Pinheiro, Hildete Prisco
We propose a homogeneity test among groups on a quadratic distance measure. The underlying mutation process in the microsatellite loci is studied using the stepwise mutation model. Asymptotic normality of the test statistic is proven under very mild regularity conditions. Resampling methods, such as jackknife, are used in the application to build confidence intervals for the difference in allelic variation between and within groups. The method is applied in a real data to test whether there are differences in the distribution of the repeated sequence among groups defined by ethnicity and alcoholism index (ALDX1).
(Georgia Institute of Technology, 2009-09-10)
Rao, Mahendra S.
Preparing cells for therapy requires developing a scalable GMP'able model for cell culture for the undifferentiated cells and for the differentiated cells derived from them. It is also important to develop testing processes and process for freezing and thawing
and selection. Using dopaminergic neuron differentiation as an example I will discuss developing a protocol for obtaining dopaminergic neurons suitable for therapy or for screening.