[00:00:00] >> Reminding everyone welcome to Nana France very nice series re we'll have non-offensive maybe not 3 present and by Professor gave ground he'll be talking about point of care diagnostics Why are the uni based isothermal amplification and paper test strips on an offense so raven our series has hosted by the Georgia Tech Institute for electronics and nanotechnology in short the i e n and I e n stands for. [00:00:33] Institute for electronics and technology I am is one of the 12 different into the discipline of research institutes on campus also i e n is a home of national nanotechnology coordinated infrastructure and then see I am sharp and southeastern nanotechnology infrastructure card are scenic supported by the National Science Foundation so the main goal of this program is to provide open access to the State of the Ark now to fabrication and characterization present these across the United States and also staff expertise. [00:01:09] And we also support educational outreach events and activities as well as these societal and ethical implications in the law for Nanotechnology So this is $200000000.00. Shared use a facility it's a fee based labs that are open to extreme no academic industry gone Mint lime tail offering a unique comprehensive nanotechnology of the search of the source so in short southeastern nanotechnology infrastructure card are in charge scenic as I said it's an n.c.i. site and c.i. is funded by n.s.f. and there are 16 and c.i. sites across the nation and scenic is one of the 16 and c.i. sites and basically scenic is a partnership of academic centers one of the Georgia Tech guy and that is us another one has joined school of nanoscience and nonaligned generic. [00:02:07] Which is an academic collaboration between the University of North Carolina Greensboro and not Carl and I ain't in your city so what do we do basically you know we provide easy user access to a wide range of comprehensive micro and nano fabrication and characterization tool sets and process capabilities along with staff expertise to the researchers in the area of nanotechnology and of course micro technology so what we offer is that we have wide range of these tool sets that's value to be around $200000000.00 and we provide all sets for research related to top down and bottoms of micro nano fabrication breed who have combined resources clean group to the deal of 30 $6000.00 pounds Kraftwerk class 1000 Plainville we also have advanced microscopic respect discovery and service analysis tools sets and there's a dedicated bio plein group which has both b s l one b. as a 2 and b. a still pretty clean rooms are available for the searchers working in the area of none of biology or in the bio area we also have computational modeling labs and laser my commissioning labs as well so how one could access our presently be is that through on site where users would be able to go to one of these sites and use the facility themselves use the tools after getting trained on the tools that they desire to use you can also remotely access office lady by sending your samples and we have dedicated staff members who will be able to provide you services and ship your samples after processing. [00:03:48] We also have training models we do have training shot courses related to micro fabrication as well as software the graphics for microfluidics and there is a special program called Catalyst grants scenic Atlas Grant Basically it provides After 1000 dollars what of free scenic Presently the axis are services and this is the proposal as welcome from new 1st. [00:04:20] Time extra academic users so number of ways that external users will be able to access our scenic facility one of best things we offer to our users is the production of staff expertise so more information is available. At the website scenic dark jacket dot edu so you can access more information on that with that said I would like to welcome. [00:04:45] Professor gave a long to come forward and there share his stopping. In this very dark and Dr Quantum is an associate professor in the Wallace culture department of biomedical engineering at Georgia Tech and Emory is also awfully good to the Institute for electronics and nanotechnology this lab pioneer stands for made of by technologies to address front here clinical challenges and cancer are going to translate rejection and Infectious Diseases. [00:05:19] On this b.s. with highest honors with u.c. Berkeley is ph d. from Cal Tech and conduct a post-doctoral research at the mit. In recognition office work Dr Wong has been hard with selective distinctions including the borrows welcome phone carrier award and the and they hedged directors new innovator award as well Dr Quan co-founded a company called a glimpse bio in 2015 and holds 20 plus issue dot pending patterns and by medical technology a let's welcome Professor want to talk was honest topic related to point of care diagnostics d.n.a. based isothermal amplification and paper test strips practical one. [00:06:09] Ok fantastic well. Thanks Paul for the for the for the introduction and this is as it's always very interesting when we learn how to adapt as a community to different things that happen in environment and having these virtual meetings I think it's fantastic allows a still to maintain a sense of. [00:06:31] You know community. But space get of coffee this is virtual and so I can be there in person and that you can you know so we're all in this together so when when Paul asked me to to share some of our work traditionally the seminars are more research heavy it's focused on you know presenting a lot of the main themes that are occurring in a lab but because of the code it endemic. [00:06:57] We like many alas were traditionally not thinking about barrel testing on pieces of paper but we shifted gears recently and especially with you know all the stuff that's going on so what I thought I do in this seminar is make it more a teaching seminar where the 1st half hour describe what what is the real testing challenges for Cove it. [00:07:21] Took Over 19 and then in the 2nd half I'll show you some of the progress that we've made in my lab in developing hopefully what we think will be a point of care paper test that could be potentially scaled to the point where it could where we could attempt to think about doing mega testing for a cause in 19 so that's the broad overview of the of the agenda today. [00:07:48] Ok so I 1st want to start off with some statistics and so this is the most recent data that we've just compiled that yesterday if you look at the total number of coping $1000.00 cases the United States it's really striking that you can see that we're still in a very strong growth phase where compared to all the other nations it's just United States United Kingdom where are the number of cases is dramatically increasing still per day and if you compare this with countries like South Korea who basically we were basically at the same place in late February early March in terms of number of cases a number of covert related deaths but what's striking is that they were able to implement many different types of measures including widespread testing which was able to so-called flatten the curve as you see in the trace on the bottom and so one of the factors that contributes to the to this sharply increased.