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IBB Distinguished Lectures

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https://hdl.handle.net/1853/70905
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Now showing 1 - 7 of 7
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Biomaterials to Program Cells in situ

2012-09-13 , Mooney, David J.

There are hundreds of clinical trials of cell therapy currently underway, but simple cell infusions lead to large-scale cell death, little control over cell fate, and a typically poor clinical outcome. We propose biomaterials to first serve as cell carriers or attractors of host cell populations, and then serve to program the cells in vivo and ultimately disperse the cells to participate in regeneration or immunotherapy.

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The Biology and Therapeutic Promise of Small RNAs

2009-10-02 , Sharp, Phillip A.

The discovery of the multiple roles of small RNAs in regulation of gene expression is a revolutionary advance in biology. MicroRNAs probably interact with mRNAs from half of all human genes. Overexpression of some microRNAs is associated with certain types of cancer while, more commonly, a reduction in microRNA levels is seen in tumors. Recent evidence suggests that the primary role of microRNAs might be to provide robustness or stability to systems. We have recently found that cytoplasmic subcellular localization of mRNAs and microRNAs is dependent upon formation of poly(ADP-ribose) and that microRNA repression is reduced under stress conditions.

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Sustaining Growth in Medical Technology

2002-11-14 , Collins, Arthur D., Jr.

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Investigation of Human Diseases at the Intersections of Engineering, Natural Sciences and Medicine

2011-09-20 , Suresh, Subra

Major advances in various branches of engineering and natural sciences, together with transformational developments in information technology, computational modeling and simulation, genetics, genomics, and nanotechnology, have provided unprecedented opportunities to explore human health and diseases at the cellular and molecular levels. Such developments have also facilitated new opportunities to study fundamental mechanistic processes with the goal of developing basic scientific understanding, new diagnostic tools, and novel therapeutics for a range of human diseases and disorders. This presentation will provide an overview of some recent accomplishments and opportunities for future exploration. Specific examples are drawn from the study of infectious diseases, hereditary blood disorders, and cancer.

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Biomedicine and Materials Science

2008-11-06 , Whitesides, George M.

George M. Whitesides joined the Department of Chemistry of Harvard University in 1982, and was Department Chairman 1986-89, and Mallinckrodt Professor of Chemistry from 1982-2004. He is now the Woodford L. and Ann A. Flowers University Professor.

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Controlling Stem Cells

2010-09-21 , McKay, Ronald D.G.

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Harnessing New Technologies to Improve Health

2003-10-16 , Sykes, Richard Brook

The Institute for Bioengineering and Bioscience’s annual Petit Distinguished Lecture features Sir Richard Sykes, rector of the Imperial College of Science, Technology and Medicine.

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