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ItemClues from Digital Radio Regarding Biomolecular Recognition(Georgia Institute of Technology, 2008-10-10) Hunt, William D.
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ItemMass-Sensitive Biochemical Microsensors(Georgia Institute of Technology, 2008-10-10) Brand, OliverA resonant microsensor platform based on disk-type microstructures vibrating in an in-plane resonance mode for chemical and biochemical sensing applications in gas and liquid environments is presented. Based on measured short-term frequency stabilities of 1.1 10^-8 in air and 2.3 10^-6 in water, mass detection limits in the low femtogram and sub-picogram, respectively, are achieved. In a biosensing application, biomolecules are immobilized on the resonator surface. Upon selective binding of analyte molecules (e.g. via antibody-antigen binding), the mass of the resonator is increased, resulting in a measurable decrease of its resonance frequency. The feasibility of liquid-phase biosensing using the disk resonators is demonstrated experimentally by detecting anti-beta-galactosidase antibody using covalently immobilized beta-galactosidase enzyme.
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ItemAnalyzing Biological Cells with Micro/Nano Engineered Systems(Georgia Institute of Technology, 2008-03-14) Frazier, A. Bruno
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ItemMedical Micro- and Nano-Technology: Case Studies in Transdermal Drug Delivery(Georgia Institute of Technology, 2008-03-14) Prausnitz, Mark R.
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ItemMicrofluidics for Magnetic Bead Based Biosensors and Modeling of Dielectrophoresis in Nanobelts(Georgia Institute of Technology, 2008-03-14) Hesketh, Peter J.