Title:
Oligo(ethylene glycol) chains: applications and advancements in biosensing
Oligo(ethylene glycol) chains: applications and advancements in biosensing
Author(s)
Bryant, Jonathan James
Advisor(s)
Bunz, Uwe H. F.
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Abstract
Oligo(ethylene glycol) groups have been used as substituents in poly(p-phenyleneethynylene)s (PPEs) to provide solubility, and to boost quantum yield. Properties such as water-solubility and increased quantum yield in aqueous solution make these conjugated systems promising for biosensory applications.
In this thesis, a PPE containing a branched ethylene glycol side chain is synthesized as part of a polymer array for glycan biosensing. I also report that the same side chain can be put to use in a red-emissive polymer to lend water solubility. Another monomeric unit, containing ethylene glycol chains, is incorporated into a PPE to create an ampiphilic polymer. The versatility of these polymers allows them to be used for a variety of purposes, some of which will be described herein.
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Date Issued
2010-10-19
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Thesis