Title:
Characterization of PVA hydrogels with regards to vascular graft development

dc.contributor.advisor Ku, David N.
dc.contributor.author Elshazly, Tarek Hassan en_US
dc.contributor.committeeMember Alexander Rachev
dc.contributor.committeeMember Vito, Raymond P.
dc.contributor.department Mechanical Engineering en_US
dc.date.accessioned 2005-03-03T22:03:43Z
dc.date.available 2005-03-03T22:03:43Z
dc.date.issued 2004-04-12 en_US
dc.description.abstract PVA hydrogels are potential biomaterials for various tissue-engineering applications. PVA hydrogels are relevant to vascular graft development due to their excellent biocompatibility and the capability to possess a wide range of mechanical properties based on compositional and processing parameters. This thesis aims to characterize some PVA hydrogels mechanically, biologically, and physically. A constitutive formulation is used for mechanical characterization, which allows for analysis of any possible stress-strain configuration applied to the material. A bovine aortic endothelial cell adhesion study under physiologic blood flow conditions comprises the biologic characterization, which gives insight into how human endothelial cells might interact with PVA hydrogels in a vascular graft application. A high-resolution SEM study is used to physically characterize the material, which furthers the understanding of the reactions of this material in vivo. These characterizations of PVA hydrogels will aid in the development of tissue-engineered products, in particular, the potential use as a vascular grafting biomaterial. en_US
dc.description.degree M.S. en_US
dc.format.extent 2392385 bytes
dc.format.mimetype application/pdf
dc.identifier.uri http://hdl.handle.net/1853/5204
dc.language.iso en_US
dc.publisher Georgia Institute of Technology en_US
dc.subject PVA en_US
dc.subject Hydrogels
dc.subject SEF
dc.subject cHRSEM
dc.subject Cell adhesion
dc.title Characterization of PVA hydrogels with regards to vascular graft development en_US
dc.type Text
dc.type.genre Thesis
dspace.entity.type Publication
local.contributor.advisor Ku, David N.
local.contributor.corporatename George W. Woodruff School of Mechanical Engineering
local.contributor.corporatename College of Engineering
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relation.isOrgUnitOfPublication c01ff908-c25f-439b-bf10-a074ed886bb7
relation.isOrgUnitOfPublication 7c022d60-21d5-497c-b552-95e489a06569
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