Printed, soft wearable and implantable electronics for wireless human health monitoring

Author(s)
Herbert, Robert
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Abstract
Wearable and implantable electronics can achieve continuous, at–home monitoring of human health and offer improvements to prevention, diagnostics, and treatments of a wide range of diseases. In particular, implantable electronics offer advantageous alternatives to the existing invasive and expensive procedures that provide incomplete views of patient health. A prevalent area of interest is vascular diseases, which in total account for 30% of deaths worldwide. Strict requirements of size, wireless operation, and compatibility with endovascular procedures have hindered the development of implantable vascular sensors. Current implantable vascular electronics are limited to bulky and rigid designs that severely limit sensing and implantation capabilities. In this dissertation, fabrication techniques, materials, mechanics, and electronics design are introduced for the development of wireless vascular sensors based upon soft capacitive sensors and an inductive vascular stent platform. Aerosol jet printing and laser machining processes are developed for fully printed sensors and a multi-material wireless stent. The integrated device is demonstrated for monitoring of aneurysms, restenosis, arterial stiffness, arterial pressure, and arterial flow. Overall the sensors and electronics achieved as a result of these studies offer a means to advance implantable electronics for continuous, wireless, and comprehensive monitoring of hemodynamics.
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Date
2022-04-26
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Text
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Dissertation
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