Brain dynamics related to short-term memory and learning
Author(s)
Helmchen, Fritjof
Advisor(s)
Editor(s)
Collections
Supplementary to:
Permanent Link
Abstract
Through the combination of in vivo optical imaging and chronic expression of genetically encoded calcium indicators it is now feasible to directly 'watch' brain activity patterns related to specific behaviors. I will introduce wide-field calcium imaging and multi-fiber photometry as two complementary methods that enable measurements across mouse neocortex and in large sets of subcortical regions, respectively. Specific patterns of brain-wide signal flow that occur in mice performing whisker-based or auditory sensory discrimination tasks will be discussed, highlighting salient patterns related to short-term memory. In addition, taking advantage of chronic measurements over weeks, I will present salient changes in brain dynamics that relate to task learning.
Sponsor
Date
2021-02-15
Extent
72:52 minutes
Resource Type
Moving Image
Resource Subtype
Lecture