Title:
Single Molecule Sensitive Probes For Detecting RNA

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dc.contributor.patentcreator Santangelo, Philip J.
dc.date.accessioned 2017-05-12T14:26:25Z
dc.date.available 2017-05-12T14:26:25Z
dc.date.filed 3/25/2010
dc.date.issued 7/22/2014
dc.description.abstract The various embodiments of the present disclosure relate generally to single molecule sensitive probes for detecting RNA, and more particularly to multivalent fluorescent probes for detecting a single molecule of RNA in a cell. The present invention includes a RNA imaging probe comprising: a multivalent core comprising a plurality of attachment sites; a plurality of RNA/DNA chimeric oligonucleotides having a specificity for a target RNA, wherein a RNA/DNA chimeric oligonucleotide is bound to an attachment site of the multivalent core; and a plurality of fluorophores, wherein a fluorophore is bound to the RNA/DNA chimeric oligonucleotide.
dc.description.assignee Georgia Tech Research Corporation
dc.identifier.cpc C12Q1/682
dc.identifier.cpc C12Q1/6841
dc.identifier.cpc C12Q1/682
dc.identifier.patentapplicationnumber 13/258830
dc.identifier.patentnumber 8785615
dc.identifier.uri http://hdl.handle.net/1853/56903
dc.identifier.uspc 536/24.3
dc.title Single Molecule Sensitive Probes For Detecting RNA
dc.type Text
dc.type.genre Patent
dspace.entity.type Publication
local.contributor.corporatename Georgia Institute of Technology
local.relation.ispartofseries Georgia Tech Patents
relation.isOrgUnitOfPublication cc30e153-7a64-4ae2-9b1d-5436686785e3
relation.isSeriesOfPublication 0f49c79d-4efb-4bd9-b060-5c7f9191b9da
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