Localized Statistics for DW-MRI Fiber Bundle Segmentation
Author(s)
Lankton, Shawn
Melonakos, John
Malcolm, James G.
Dambreville, Samuel
Tannenbaum, Allen R.
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Abstract
We describe a method for segmenting neural fiber bundles in diffusion-weighted magnetic resonance images (DW-MRI). As these bundles traverse the brain to connect regions, their local orientation of diffusion changes drastically, hence a constant global model is inaccurate. We propose a method to compute localized statistics on orientation information and use it to drive a variational active contour segmentation that accurately models the non-homogeneous orientation information present along the bundle. Initialized from a single fiber path, the proposed method proceeds to capture the entire bundle. We demonstrate results using the technique to segment the cingulum bundle and describe several extensions making the technique applicable to a wide range of tissues.
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Date
2008-06
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Text
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Proceedings