The Neural Circuits Underlying Short-term Memory

Svoboda, Karel

Title:

The Neural Circuits Underlying Short-term Memory

dc.contributor.author	Svoboda, Karel
dc.contributor.corporatename	Georgia Institute of Technology. Neural Engineering Center	en_US
dc.contributor.corporatename	Howard Hughes Medical Institute	en_US
dc.date.accessioned	2017-10-13T16:21:02Z
dc.date.available	2017-10-13T16:21:02Z
dc.date.issued	2017-10-02
dc.description	Presented on October 2, 2017 at 11:00 a.m. in the Krone Engineered Biosystems Building, Room 1005.	en_US
dc.description	Dr. Karel Svoboda is a group leader at the Janelia Research Campus. He was an HHMI investigator at Cold Spring Harbor Laboratory from 2000 to 2006.	en_US
dc.description	Runtime: 60:00 minutes	en_US
dc.description.abstract	Our goal is to uncover the principles by which cortical circuits perform fundamental computations, from perception to action. Cortex is parcellated into areas with distinct function and local circuits. Cortical areas associate into mesoscale circuits with other cortical and subcortical areas via long-range connections. Information is represented by action potentials in widely distributed ensembles of neurons. What are the mechanisms shaping these neural representations, and how do the representations drive behavior? We have begun to address both questions in behaving mice in the context of motor planning and short-term memory. Motor planning plays key roles in decision-making and motor control. Apart from reflexes, movements are dynamically programmed to achieve a specific goal. Many movements are too rapid for online corrections. Movements that are preceded by periods of motor planning are faster and more accurate than in the absence of planning. Motor planning is also a prospective form of short-term memory that links past events and future movements. During motor planning, neurons in motor cortex show persistent activity related to specific movements, long before movement onset, in the absence of sensory input. I will present our studies on how neural circuits maintain this selective persistent activity and how this activity relates to future behavior.	en_US
dc.format.extent	60:00 minutes
dc.identifier.uri	http://hdl.handle.net/1853/58832
dc.language.iso	en_US	en_US
dc.relation.ispartofseries	GT Neuro Seminar Series
dc.subject	Brain	en_US
dc.subject	Neurophysiology	en_US
dc.title	The Neural Circuits Underlying Short-term Memory	en_US
dc.type	Moving Image
dc.type.genre	Lecture
dspace.entity.type	Publication
local.contributor.corporatename	Neural Engineering Center
local.relation.ispartofseries	GT Neuro Seminar Series
relation.isOrgUnitOfPublication	c2e26044-257b-4ef6-8634-100dd836a06c
relation.isSeriesOfPublication	608bde12-7f29-495f-be22-ac0b124e68c5