Title:
Development of a combined angiography and late gadolinium enhancement MR sequence

dc.contributor.advisor Oshinski, John N.
dc.contributor.author Lam, Adrian
dc.contributor.department Biomedical Engineering (Joint GT/Emory Department)
dc.date.accessioned 2017-01-11T14:00:30Z
dc.date.available 2017-01-11T14:00:30Z
dc.date.created 2015-12
dc.date.issued 2015-11-13
dc.date.submitted December 2015
dc.date.updated 2017-01-11T14:00:30Z
dc.description.abstract With the rapid growth of catheter-based interventional cardiology procedures, knowledge of the vasculature surrounding the heart relative to the distribution of scar tissue can provide important information for procedural planning and appropriate patient selection. We developed an MR sequence that would acquire inherently co-registered angiography and scar images by Sharing K-space (SharK) and created image processing methods for a combined display. The SharK sequence was validated by comparing its performance against its respective gold standards for angiographic and scar imaging. The SharK sequence was applied in patients with previous myocardial infarction to create a combined coronary vein and scar display that could be used for pre-procedural planning in patients undergoing Cardiac Resynchronization Therapy. The SharK sequence was also applied in patients post-Pulmonary Vein Isolation to quantify the amount of scar encircling the pulmonary veins by developing a pulmonary vein bullseye. The pulmonary vein bullseyes can be used to improve the ablation process or guide repeat ablations.
dc.description.degree Ph.D.
dc.format.mimetype application/pdf
dc.identifier.uri http://hdl.handle.net/1853/56212
dc.publisher Georgia Institute of Technology
dc.subject Magnetic resonance imaging
dc.subject Cardiac resynchronization therapy
dc.subject Atrial fibrillation
dc.subject Pulmonary vein isolation
dc.subject Electrophysiology
dc.subject Image processing
dc.title Development of a combined angiography and late gadolinium enhancement MR sequence
dc.type Text
dc.type.genre Dissertation
dspace.entity.type Publication
local.contributor.advisor Oshinski, John N.
local.contributor.corporatename Wallace H. Coulter Department of Biomedical Engineering
local.contributor.corporatename College of Engineering
relation.isAdvisorOfPublication 05472fe1-6d57-4489-af83-42115a3f55cc
relation.isOrgUnitOfPublication da59be3c-3d0a-41da-91b9-ebe2ecc83b66
relation.isOrgUnitOfPublication 7c022d60-21d5-497c-b552-95e489a06569
thesis.degree.level Doctoral
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