Title:
Variants Of Ancestral Uricases And Uses Thereof
Variants Of Ancestral Uricases And Uses Thereof
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Abstract
The present invention provides uricases and methods of their production and use in reducing the amount of uric acid in a subject. The present invention further provides methods employing a uricase of this invention in the treatment and/or prevention of hyperuricemia, gout, tumor lysis syndrome and/or hypertension in a subject.
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1/27/2015
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Patent