Title:
Developing aerosol jet printable regenerated silk fibroin solutions

dc.contributor.advisor Harris, Tequila A. L.
dc.contributor.author Xiao, Yuhan
dc.contributor.committeeMember Kalaitzidou, Kyriaki
dc.contributor.committeeMember Yao, Donggang
dc.contributor.department Mechanical Engineering
dc.date.accessioned 2019-05-29T14:04:52Z
dc.date.available 2019-05-29T14:04:52Z
dc.date.created 2019-05
dc.date.issued 2019-04-30
dc.date.submitted May 2019
dc.date.updated 2019-05-29T14:04:52Z
dc.description.abstract Regenerated silk fibroin (RSF) solutions have gained a lot of attention due to its strong mechanical properties, biocompatibility and biodegradability. To exploit these unique properties, for applications such as drug delivery, packaging, biosensor, and wound treatment non-contact, maskless printing methods are highly desirable, such as inkjet printing (IJP). However, IJP is prone to clogging and typically additives, which alter the chemistry of the solution, are required to successful deposition. In this work, a framework for using aerosol jet printer (AJP) to fabricate RSF solutions derived from cocoons of the silkworm is developed. A unique combination of degumming, dissolving and dialysis conditions is required to prepare an aerosol jet printable RSF solution. It has been found that slight changes in those steps can lead to gelation or printing defects. Even so, it has been shown that additives are not required for AJP RSF solutions, and when added have a negative impact on the printed pattern. From the developed operating window, it has been shown that outside the optimum ranges, the patterns will be subjected to several defects including discontinuities, pooling and cloudiness. An artifact of AJP known as overspray has been found to be an uncontrolled phenomenon that can be reduced by increasing sheath rate. The results of this investigation introduce the feasibility of AJP patterns from RSF solutions.
dc.description.degree M.S.
dc.format.mimetype application/pdf
dc.identifier.uri http://hdl.handle.net/1853/61312
dc.publisher Georgia Institute of Technology
dc.subject Liquid drop jetting
dc.subject Aerosol jet printing
dc.subject Regenerated silk fibroin
dc.subject Hybrid inorganic/organic
dc.subject Protein coatings
dc.title Developing aerosol jet printable regenerated silk fibroin solutions
dc.type Text
dc.type.genre Thesis
dspace.entity.type Publication
local.contributor.advisor Harris, Tequila A. L.
local.contributor.corporatename George W. Woodruff School of Mechanical Engineering
local.contributor.corporatename College of Engineering
relation.isAdvisorOfPublication 9e668e9c-c468-4e77-a58c-462f72af725a
relation.isOrgUnitOfPublication c01ff908-c25f-439b-bf10-a074ed886bb7
relation.isOrgUnitOfPublication 7c022d60-21d5-497c-b552-95e489a06569
thesis.degree.level Masters
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