Routes to Chiral Purity Involving Crystallization
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Abstract
Chiral purity has become an increasingly important characteristic of many specialty chemicals, especially
pharmaceuticals. Manufacturers seeking chiral purity have two choices: (1) utilize syntheses that directly
yield such purity or (2) separate and purify a desired stereoisomer from a mixture containing two or more
isomers. This presentation will highlight the use of crystallization in meeting the challenges of such
separations. Particular emphasis will be given to the role of nucleation in determining the identity of the
species produced and to controlling system conditions so that nucleation and growth mechanisms may be
manipulated to influence the process outcome.
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Date
2013-04-25
Extent
59:41 minutes
Resource Type
Moving Image
Resource Subtype
Lecture