Molecules With Potent DHFR Binding Affinity And Antibacterial Activity

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9920058.pdf (2.89 MB)
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http://hdl.handle.net/1853/65440
Abstract
7-(substituted) derivatives of 7H-pyrrolo[3,2-f]-quinazoline-1,3-diamines, derivative thereof, and methods of using them are provided. The pharmaceutical formulations prepared from the compounds can be used to treat a variety of conditions, which include, but are not limited to bacterial and fungal infections. The compounds can also be used as a sterilizing or disinfecting agent.
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3/20/2018
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