Title:
The Effectiveness of Sealants in Managing Carious Lesions

dc.contributor.author Griffin, S. O.
dc.contributor.author Oong, E.
dc.contributor.author Kohn, W.
dc.contributor.author Vidakovic, Brani
dc.contributor.author Gooch, B. F.
dc.contributor.author Bader, J.
dc.contributor.author Clarkson, J.
dc.contributor.author Fontana, M. R.
dc.contributor.author Meyer, D. M.
dc.contributor.author Rozier, R. G.
dc.contributor.author Weintraub, J. A.
dc.contributor.author Zero, D. T.
dc.contributor.corporatename Georgia Institute of Technology. Dept. of Biomedical Engineering
dc.contributor.corporatename Emory University. Dept. of Biomedical Engineering
dc.contributor.corporatename Centers for Disease Control and Prevention (U.S.). Dental Sealant Systematic Review Work Group
dc.contributor.corporatename Centers for Disease Control and Prevention (U.S.). Division of Oral Health. Surveillance, Investigations, and Research Branch
dc.contributor.corporatename University of North Carolina at Chapel Hill. School of Dentistry
dc.contributor.corporatename Indiana University School of Dentistry. Oral Health Research Institute
dc.contributor.corporatename University of Dundee. Dental Health Services Research Unit
dc.contributor.corporatename American Dental Association
dc.contributor.corporatename University of California, San Francisco. Center to Address Disparities in Children’s Oral Health
dc.contributor.corporatename University of California, San Francisco. School of Dentistry
dc.date.accessioned 2008-11-25T17:50:27Z
dc.date.available 2008-11-25T17:50:27Z
dc.date.issued 2007
dc.description.abstract A barrier to providing sealants is concern about inadvertently sealing over caries. The objective of this meta-analysis was to examine whether sealants are effective in preventing caries progression. Methods: Our search of electronic databases for comparative studies examining caries progression in sealed permanent teeth located 1905 unique records. We ordered 311 articles that met the inclusion criteria. We used a random-effects model to estimate percentage reduction in caries progression in sealed carious teeth compared to not-sealed carious teeth. Findings: Six studies including 4 randomized-controlled trials (RCT) were used in the analysis (1090 surfaces, 840 teeth, and 384 persons). The median annual percentage of non-cavitated lesions progressing was 2.6% for sealed and 12.6% for unsealed carious teeth. The summary prevented fraction for RCT was 71.3% (95%CI: 52.8%-82.5%; no observed heterogeneity). Conclusions: Sealing non-cavitated caries in permanent teeth reduces caries progression by over 70% up to 5 years after placement. en
dc.identifier.uri http://hdl.handle.net/1853/25831
dc.language.iso en_US en
dc.publisher Georgia Institute of Technology en
dc.relation.ispartofseries Biomedical Engineering Technical Report ; 04/2007 en
dc.subject Pit and fissure sealants en
dc.subject Caries en
dc.subject Dental caries prevention
dc.title The Effectiveness of Sealants in Managing Carious Lesions en
dc.title.alternative Effectiveness of sealing caries
dc.type Text
dc.type.genre Technical Report
dspace.entity.type Publication
local.contributor.author Vidakovic, Brani
local.contributor.corporatename Wallace H. Coulter Department of Biomedical Engineering
local.contributor.corporatename College of Engineering
relation.isAuthorOfPublication 1463fd97-3d52-4269-afac-97f6f7f46fcd
relation.isOrgUnitOfPublication da59be3c-3d0a-41da-91b9-ebe2ecc83b66
relation.isOrgUnitOfPublication 7c022d60-21d5-497c-b552-95e489a06569
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