Title:
The RNA Ontology Consortium: An Open Invitation to the RNA Community

dc.contributor.author Leontis, Neocles B. en_US
dc.contributor.author Altman, Russ B. en_US
dc.contributor.author Berman, Helen M. en_US
dc.contributor.author Brenner, Steven E. en_US
dc.contributor.author Brown, James W. en_US
dc.contributor.author Engelke, David R. en_US
dc.contributor.author Harvey, Stephen C. en_US
dc.contributor.author Holbrook, Stephen R. en_US
dc.contributor.author Jossinet, Fabrice en_US
dc.contributor.author Lewis, Suzanna E. en_US
dc.contributor.author Major, François en_US
dc.contributor.author Mathews, David H. en_US
dc.contributor.author Richardson, Jane S. en_US
dc.contributor.author Williamson, James R. en_US
dc.contributor.author Westhof, Eric en_US
dc.contributor.corporatename Bowling Green State University. Dept. of Chemistry en_US
dc.contributor.corporatename Bowling Green State University. Center for Biomolecular Sciences en_US
dc.contributor.corporatename Stanford University. Medical Center en_US
dc.contributor.corporatename Stanford University. Medical Informatics en_US
dc.contributor.corporatename Rutgers University. Dept. of Chemistry and Chemical Biology en_US
dc.contributor.corporatename University of California, Berkeley. Dept. of Plant and Microbial Biology en_US
dc.contributor.corporatename North Carolina State University. Dept. of Microbiology en_US
dc.contributor.corporatename University of Michigan. Dept. of Biological Chemistry en_US
dc.contributor.corporatename Georgia Institute of Technology. School of Biology en_US
dc.contributor.corporatename Lawrence Berkeley National Laboratory. Dept. of Structural Biology en_US
dc.contributor.corporatename University of California, Berkeley. Dept. of Molecular and Cell Biology en_US
dc.contributor.corporatename Université de Montréal. Département d’Informatique et de Recherche Opérationnelle en_US
dc.contributor.corporatename University of Rochester. Medical Center en_US
dc.contributor.corporatename Duke University. Dept. of Biochemistry en_US
dc.contributor.corporatename Université Louis Pasteur de Strasbourg I en_US
dc.contributor.corporatename Institut de biologie moléculaire et cellulaire en_US
dc.date.accessioned 2013-10-07T18:55:26Z
dc.date.available 2013-10-07T18:55:26Z
dc.date.issued 2006-04
dc.description ©2006 RNA Society. Published by Cold Spring Harbor Laboratory en_US
dc.description DOI: 10.1261/rna.2343206 en_US
dc.description.abstract The aim of the RNA Ontology Consortium (ROC) is to create an integrated conceptual framework—an RNA Ontology (RO)—with a common, dynamic, controlled, and structured vocabulary to describe and characterize RNA sequences, secondary structures, three-dimensional structures, and dynamics pertaining to RNA function. The RO should produce tools for clear communication about RNA structure and function for multiple uses, including the integration of RNA electronic resources into the Semantic Web. These tools should allow the accurate description in computer-interpretable form of the coupling between RNA architecture, function, and evolution. The purposes for creating the RO are, therefore, (1) to integrate sequence and structural databases; (2) to allow different computational tools to interoperate; (3) to create powerful software tools that bring advanced computational methods to the bench scientist; and (4) to facilitate precise searches for all relevant information pertaining to RNA. For example, one initial objective of the ROC is to define, identify, and classify RNA structural motifs described in the literature or appearing in databases and to agree on a computer-interpretable definition for each of these motifs. To achieve these aims, the ROC will foster communication and promote collaboration among RNA scientists by coordinating frequent face-to-face workshops to discuss, debate, and resolve difficult conceptual issues. These meeting opportunities will create new directions at various levels of RNA research. The ROC will work closely with the PDB/NDB structural databases and the Gene, Sequence, and Open Biomedical Ontology Consortia to integrate the RO with existing biological ontologies to extend existing content while maintaining interoperability. en_US
dc.identifier.citation Neocles B. Leontis, Russ B. Altman, Helen M. Berman, Steven E. Brenner, James W. Brown, David R. Engelke, Stephen C. Harvey, Stephen R. Holbrook, Fabrice Jossinet, Suzanna E. Lewis, François Major, David H. Mathews, Jane S. Richardson, James R. Williamson, and Eric Westhof, “The RNA Ontology Consortium: An open invitation to the RNA community,” RNA 2006. 12: 533-541. en_US
dc.identifier.doi 10.1261/rna.2343206
dc.identifier.issn 1355-8382
dc.identifier.uri http://hdl.handle.net/1853/49185
dc.language.iso en_US en_US
dc.publisher Georgia Institute of Technology en_US
dc.publisher.original Cold Spring Harbor Laboratory Press en_US
dc.subject Biological ontology en_US
dc.subject RNA en_US
dc.subject sequence alignments en_US
dc.subject 3D structure en_US
dc.subject RNA motifs en_US
dc.title The RNA Ontology Consortium: An Open Invitation to the RNA Community en_US
dc.type Text
dc.type.genre Article
dspace.entity.type Publication
local.contributor.corporatename College of Sciences
local.contributor.corporatename School of Biological Sciences
relation.isOrgUnitOfPublication 85042be6-2d68-4e07-b384-e1f908fae48a
relation.isOrgUnitOfPublication c8b3bd08-9989-40d3-afe3-e0ad8d5c72b5
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