Title:
Trans-skull Ultrasound for Imaging and Therapy
Trans-skull Ultrasound for Imaging and Therapy
Author(s)
Schoen, Scott J.
Advisor(s)
Arvanitis, Costas
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Abstract
Ultrasound has emerged as a novel modality for the treatment and imaging of brain diseases. When enhanced by circulating microbubble agents, which scatter sound and vibrate in response to the incident ultrasound, it can enable a range of new therapeutic interventions and open new possibilities for imaging. Despite these advancements, the skull remains a major challenge both for therapy and imaging. This work proposes methods for fast, frequency-selective passive reconstruction of the acoustic field through human skull with applications including improved targeting for exploitation of nonlinear acoustic effects in the brain, controlling the microbubble dynamics, and super-resolution imaging.
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Date Issued
2020-12-03
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Resource Type
Text
Resource Subtype
Dissertation