Title:
Regulation of Galactosylceramide Biosynthesis

dc.contributor.advisor Merrill, Alfred H.
dc.contributor.author Kollmeyer, Jessica Elaine en_US
dc.contributor.committeeMember M. Cameron Sullards
dc.contributor.committeeMember Sewer, Marion B.
dc.contributor.department Biology en_US
dc.date.accessioned 2006-09-01T19:43:42Z
dc.date.available 2006-09-01T19:43:42Z
dc.date.issued 2006-07-12 en_US
dc.description.abstract An important branchpoint of mammalian sphingolipid metabolism occurs at the step where ceramides are glycosylated to glucosylceramide (GlcCer) versus galactosylceramide (GalCer), which are precursors of all mammalian glycosphingolipids. Relatively few studies have focused on this branchpoint because these monohexosylceramides are somewhat difficult to resolve chromatographically and because molecular biology tools have only recently become available to follow expression of these genes. The goal of this thesis is to better understand the mechanisms of cell regulation determining galactosylceramide synthesis. en_US
dc.description.degree M.S. en_US
dc.format.extent 257032 bytes
dc.format.mimetype application/pdf
dc.identifier.uri http://hdl.handle.net/1853/11630
dc.language.iso en_US
dc.publisher Georgia Institute of Technology en_US
dc.subject Galacotsylceramide en_US
dc.subject Glycosphingolipids
dc.subject Sphingolipids
dc.title Regulation of Galactosylceramide Biosynthesis en_US
dc.type Text
dc.type.genre Thesis
dspace.entity.type Publication
local.contributor.advisor Merrill, Alfred H.
local.contributor.corporatename College of Sciences
local.contributor.corporatename School of Biological Sciences
relation.isAdvisorOfPublication e2cc92fe-a320-49d9-a516-d6badc8d0e75
relation.isOrgUnitOfPublication 85042be6-2d68-4e07-b384-e1f908fae48a
relation.isOrgUnitOfPublication c8b3bd08-9989-40d3-afe3-e0ad8d5c72b5
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