Title:
Label Space: A Coupled Multi-shape Representation

dc.contributor.author Malcolm, James G.
dc.contributor.author Rathi, Yogesh
dc.contributor.author Shenton, Martha E.
dc.contributor.author Tannenbaum, Allen R.
dc.contributor.corporatename Brigham and Women's Hospital. Psychiatry Neuroimaging Laboratory
dc.contributor.corporatename Georgia Institute of Technology. School of Electrical and Computer Engineering
dc.date.accessioned 2009-07-31T19:49:55Z
dc.date.available 2009-07-31T19:49:55Z
dc.date.issued 2008-09
dc.description The original publication is available at www.springerlink.com: http://dx.doi.org/1 10.1007/978-3-540-85990-1_50
dc.description DOI: 10.1007/978-3-540-85990-1_50
dc.description.abstract Richly labeled images representing several sub-structures of an organ occur quite frequently in medical images. For example, a typical brain image can be labeled into grey matter, white matter or cerebrospinal fluid, each of which may be subdivided further. Many manipulations such as interpolation, transformation, smoothing, or registration need to be performed on these images before they can be used in further analysis. In this work, we present a novel multi-shape representation and compare it with the existing representations to demonstrate certain advantages of using the proposed scheme. Specifically, we propose label space, a representation that is both flexible and well suited for coupled multishape analysis. Under this framework, object labels are mapped to vertices of a regular simplex, e.g. the unit interval for two labels, a triangle for three labels, a tetrahedron for four labels, etc. This forms the basis of a convex linear structure with the property that all labels are equally spaced. We will demonstrate that this representation has several desirable properties: algebraic operations may be performed directly, label uncertainty is expressed equivalently as a weighted mixture of labels or in a probabilistic manner, and interpolation is unbiased toward any label or the background. In order to demonstrate these properties, we compare label space to signed distance maps as well as other implicit representations in tasks such as smoothing, interpolation, registration, and principal component analysis. en
dc.identifier.citation James Malcolm, Yogesh Rathi, Martha E. Shenton, Allen Tannenbaum, "Label Space: A Coupled Multi-Shape Representation," Medical Image Computing and Computer-Assisted Intervention – MICCAI 2008, 11th International Conference, New York, NY, USA, September 6-10, 2008, Proceedings, Part II, Dimitris Metaxas, Leon Axel, Gabor Fichtinger, and Gábor Székely, editors, Lecture Notes in Computer Science, Vol. 5242 (2008) 416-424 en
dc.identifier.isbn 978-3-540-78274-2
dc.identifier.issn 0302-9743
dc.identifier.uri http://hdl.handle.net/1853/29402
dc.language.iso en_US en
dc.publisher Georgia Institute of Technology en
dc.publisher.original Springer Verlag
dc.subject Medical image analysis
dc.subject Multishape analysis
dc.subject Label space
dc.title Label Space: A Coupled Multi-shape Representation en
dc.type Text
dc.type.genre Post-print
dspace.entity.type Publication
local.contributor.corporatename Wallace H. Coulter Department of Biomedical Engineering
relation.isOrgUnitOfPublication da59be3c-3d0a-41da-91b9-ebe2ecc83b66
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