Our next president presentation.

Then they want to complete their first
session is we used to hold yourself

to such pleasure to be here and
stiff this ground presuming that this is

what is going to do and so

we will resume working and
you come here and say

thank you for coming today like
Dr Who sat my name is Lisa and

we're going to present in our study
that ten percent that's yours and

stiffness properties in the form
of a clinical trial and

it's laboratory under the advice of
Dr Sears now as you can see we're

going to discuss the background of that
aggression about ready to do this or

specific and or
test apparatus design an experiment.

We're going to talk about some
of our results in discussion

and some funding and.

Background of your study where
they have been used to treat many

different the disorders for a pretty
long period of time actually interface

with the structures and structures
of the is not very well understood.

There have been some studies that look at
the declaration properties of the the new

focus and
it also has been utilized to look at

the imaging has now been formed
extensively in other areas that

are speaking specific to you know the
stiffness of the players during very very.

Independently of the behavior of
scientists you do the mission and

displacement of the under
new moves to be used.

It will be in these conditions
are steamy to maintain privacy.

The first was that we expected that
the plane or soft tissues would be stepped

there in week very very due to the
increased tension tension of the plane in

the year that the greater
defamation it's so

easy to choose very thin and weak in

order to test the reconstruction device
to apply new forces to the plan or

services of that video to the stiffness in

defamation a significant amount
of time was spent developing

a complete set up to test
these have these included

the apparatus into stance one for
weight bearing and one for

nominally vary the force allocation
apparatus is in the image to the right.

Uses stepper motor to drive when
you're actually to have a good sound

attached to it.

Control that stuff and that was mounted
to the plate that have been for

it through the transducer
into the third and

as I mentioned previously we
also had to make two separate

frames which this apparatus could
be mounted one week during and

one from the very in and
set up as you can see union.

We used to reject frame the side
that enabled us to raise and

lower the apparatus on
the subjects that size of me

to ensure that we made in the same
position throughout all the testing and

students people which is subject to leave
room for the testing as instructed and

the device was set to the correct paper
deficit for the weight bearing condition.

We built an elevated platform that allows.

The rat is to be known to be the subject
of the subtext that all the tribes

of the records in the X. and Y.
directions been the subject

approximately of the ultrasound
transducers to the truth.

Jews are to be driven through
the ple into the During testing so

determine to the index of each of the
vigils in order to characterize the feat

that we are studying resentment at fifty
percent of the length from the trees and

projecting from my section of the heels
of the space between the second and

third rays was drawn the intersection of
these two lines is the location at which

we perform all over to have secured
sets of weeping her new year and

its position to ensure that is
made the skin deserving and

the Kurds and tediously is activated

at a speed of zero point zero six
three five centimeters per second.

The computer started to sound

transducer returned to the same starting
position at the beginning of the trial and

the video recording history and

total force of hearing in the weight
room decisions reached and

then everything is sound tediously staff
previous studies were used to determine

the acceptable maximum force is applied
to return to the starting position and

the process was completed
a little ten times for

each of the three test conditions
which were very stance and

we bring in single total of
thirty trials for each side.

Through the results in this race.

We're able to test for subjects in
our pilot study projects we have for

I review this lectures that the poster
index three subjects ability to read and

the question X. can range from
negative to positive with negative

and values indicating a pro need
to start from zero to five.

So you can see here
the subjects want three and

four values that fell in the normal range.

Well subject to kind of that and
we've also provided to represent

the normal subjects alongside
the related subjects for comparison

A familiar with the orientation and
imaging this animation of the location

as you can see an ultrasound image
is just a vertical slice of the myth

that not only described previously it's
important to note that we are now looking

at these images from your view
that we did test the right.

But the subject.

This is the image from the previous lie
it's a right angle from the post you hear

the left and right is left the planter's

which is where you find the force and
it goes from there point out

some of the structures of interests
there is the former is the key

for us is this your heart
rate plan is this mall or

muscle and
this circle is the lateral plantar artery.

Now as far as the source.

It's just for some a Y.
axis displacement is in the X.

axis and
the slope of the line is still that hires.

Is a greater step and you get the Beijing
burgers there is usually a non-linear

region initially when there's little or so
use and it shifts to a more linear system.

This is just a representative
video of the normally very

scene here that has the force
by the press against the planes

are you can see any good holes and
that will eventually force the.

Let's watch that.

All right so I mentioned before we had
three subjects that fell in the normal

range for the past year and they all
have very similar curves so this is

representative of ones that on again
this is of course displays the graph Y.

axis force accesses displacement and these
values to the meet stiffness of the ten

trials we did they are ours are the
standard deviations of those ten trials.

The blue line is the only
bearing condition.

The red line is the weight
bearing in Dublin and

green is the way bearing
in single condition.

It's easy to see that the not a very
interesting has a much lower stiffness and

you have the weight bearing in this.

Additionally you can see that single
eye wavering results in a much stiffer

and it's only very patient.

You also notice that they don't weigh
bearing that he has much smaller

standard deviations than even
the wavering conditions.

This is because weight bearing
is only a while as that extended

innermost circle simply
adjusting the Cubans the right.

So there's naturally more close
to a shoe in the tissue since.

Thank you very much.

This is a pilot study and we have not
completed statistical analysis but

we are fairly confident that
the state is just a models and

once that Jackson had
printed the plaster objects

the graph is the same graph
is on the previous slide but

you can see that it's a single and
double in week very markedly different.

They're actually quite similar.

And I don't exactly sure why this is but

maybe a different postures their
highest stiffness in any week or

so one of the long term
objectives of the studies to

improve our understanding of how quarter
of those you put tissue characteristics.

Because we are subject to the per needed
co-pastor and one of the common or

the ticket or ventures that is separate
but is to realize we are just less.

I needed position to do a little case
study with this subject with the need of

partial labor with the meal and
March elevated and

that we felt OK to the customer all that
she which is actually really the material

used to cross that test and
we needed a very rigid material to stand

still transducer So that's why we went
to the nontraditional material for

this that or those and
then look at the subject.

Stands on their lives and up to ten
child bearing and they described.

This time graph actually shows our
results are like a little case

study in fourth place and
graph this before and

it compares our control which
was very good double and read.

So you can test addition in purple which
is the cause of the old record those you

can see this is notably
decreased in the planner so

to use this data we demonstrated
that at least with this subject.

We're at those it's stiffness
the planners of tissues are not and

this is a material and so
result of probably be less drastic with

more traditional materials and also
results will be very with other subjects.

So now we're going to switch
gears a little bit and

more since we chose to
take measurements and

they're still here to read which is

then purple is a green and
superficial fashion that is in blue.

We took these measurements and zero
percent twenty five fifty seventy five and

one hundred percent of
the fourth supply and

to time constraints we're only able
to complete these measurements for

one subject in three trials of each
condition and the interest of time today.

We will be presenting your results and
to keep away.

I think it will be.

Reply to reliably measuring
the structures on the older self video.

This is just collimator a day that
I don't attempt to cuboid And

again the grammar shown on the ultrasound
image at the left on this graph a Y.

axis is the change in that and the X.
axis is the force applied and as before.

I'm not wavering it's blue the only
way bearings red and single and

we vary is green.

You can see a very had much greater change

in that which translates into more
compression of the tissues that way but

this is because they're not laboring
had much lower stiffness and so

they're able to compress more.

However we do have a very
large standard deviation.

But we can still easily distinguish
between the normally very and

to a very conditions.

However these results are only for
one subject.

It's just for
the reading data to summarize our results.

The stiffness the planner and the tissues
varies notably between I'm wavering and

weight bearing with the weight bearing
condition having stiffer tissues this

confirm this is that weight bearing
would have to produce use then a very

integrated a similar stiffness
between single and stance.

While normal exhibited notable differences
between the two weight bearing conditions.

Our results show for it but are those its
current decreased openness in the plan or

mid-foot tissues in the subject to
the permeated But given these results.

What are those appear to have the capacity
to alter the stiffness properties of

herself to use the results of the study
suggests that the characteristic

properties of tissues can be measured and
some tissues appear to be

influencing that or of the Z's used in
this also appears to be very promising.

So it would be valuable to pursue
these that evaluate this misbehavior.

So how could all this be relevant.

Properties of these properties

that are based in fact that the

first techniques

and ultimately

for this work

of every three years.

Thank you very much.

What are your very very very serious for

this because this is just pilot work but

you've got a very beautiful.

Well you

know we didn't actually look at that but
that's definitely something we should we

actually didn't take any video for
that testing that that's something

you were

five or

so people right.

Structures in the OK so

we could take in that we weren't actually
determine a separate misses for each

one of

those this reduces

our limited.

I'm going to know the answer you
mean I actually don't know yet but

what we do know is that he was so
different.

Lou.

In some instances when something is wonky
we may want to know after each step down.

I'm sure we can we can have it here and.

So this is probably going
to play short of time for

people at least that's very clear right

now that

they want to do next year.

Yeah.

Actually you can see that
this is this will be for

years to characterise the uber
healthy stuff you think of it but

obviously the Saudis are going to free
these properties in their entirety.

And yes we are very interested.

Obviously you know as well so we

are subject to your bluster is
probably your only appropriated that

we there is we believe this
is going to transition into

actually placing sheet
components to emulate those.

So we still be able to measure
the stiffness even the words around

with it how that will play which is still

less jobs or dead.