[00:00:00] >> Thank you. I'm really delighted to be here not only are you going to say this was I finally get to spend here and see the things you're doing now which were for a number of years for her undergraduate student to be one here. He writes this We also get a good easy summer and he writes here with me here and here I'll say I really want to spend some time on you. [00:00:45] Well we were telling you where literally almost ten years and something about it. I really was just so patient. Why are we here all radical right and the reason I ask that is although working on this technology for the last ten years even as recently as three years ago. [00:01:07] No one was voted for this we couldn't even get people to list. This is America where the number of other beings and now three of your readers later the first real political crisis. Everywhere. This question is are we moving ahead. Rarely are we getting away with it and hope you'll join me in exploring question what I really want to do when out was the oldest and really. [00:01:45] That's right. Steve is going to do it. So it is a growing field and nineteen and a would personally. There were twenty patients feel last year alone the rover who came out with and who do the self paced already and already this year. You did it was a loser many more. [00:02:24] So it's a rapidly growing field and everyone's religion spanned really want to explore. So I'm going to go through the concept really of your pre-planned was only and then talk about what we're going to ask what we think the next few years. Look like this in mind that it was so obviously the reason it was party and this is this is where you should go along with us and backs it was really really really patients every year at us and you will get it repaired the damage there isn't my second marriage was going to happen on years. [00:03:17] What was going to be here. So I like to think about you for the information as I knew she was that we could get through dysfunction and as a cascade to resit disorder where we really if you think about what's going on. You have to see and what are you criticise how are you trying to do more with yourself again get remodelling for yourself that I'm less functional this vicious cycle. [00:03:50] So we decided to do was really decide what you can't walk that's like and I think it's going to be providing more sales. So you can use the cells then you to mediate on the repair of the party of Tripoli and eugenicist or perhaps to do a little testily. [00:04:10] There are a few genes that are all be used. So this is a very straightforward not simple script forward that we focus on we focused on the right. Milan still see the individual cells that exist for the muscle expanding the cells in the right and you're working in cells in true. [00:04:42] Regional party. I would submit that this group heritage trying to do the kinds of honey engineering and they're trying to deal with higher native life for your mind for you where the cells are not you're simply change the functional size no longer frankly you did you this was like a Genesis Mandisa dealing with an end or are you actually going to store policy you want your book was younger is not going to be there years. [00:05:19] You can use this in the absence of an army which I think is going to go over the right gene therapy trials. And yet Yeah you really are not likely to hear actually for me it was like was he trying to put in huge numbers of cells. How did he she can use this really nice to get the functional repaired the size nutrients. [00:05:50] If you're trying to do here are hiring him I heard him I submitted my eyeglasses. Plus or minus grew back to sneeze and I was wounded. Yes. In addition birth factors alone make your own marriage rights for homosexuals to be sufficient. And at least in Europe and now I actually need to ask. [00:06:09] There's a bone or clinical trial that has been initiated to simply look at transplanting more bone marrow putting in Genesis for functional we care skinny triumphal cells. We focus primarily on skeletal I am glad you might you might ask why are you science rebuilder Rice chromosomes and that are there again the goal is a contractual cell so what purpose. [00:06:39] Cells to use. Why not simply induce native Purdy's like deliberation. Well as many of you probably already know the name you said to do that. And here's your party sides actually need you to provide a nucleus to replicate in the end but my wish my record number of bruises spend many years proving criticize underside nieces and it seems to be a lot. [00:07:06] We simply can't get them to divide the cells that are pretty sites that we can't get to my original years in the cells and back in the original so when you can go and pick them up. The other reason that meat that many people don't talk about Don't think about is a much more physiologic reason. [00:07:29] And now to this you're dealing with an informative region of very soon trying to transplant cells and their reach for you or your sites and their ninety nine percent. As I was going to die second hearing through stevia to really essentially she herself would rather party sites we did these do this so instead we have chosen to repopulate the scar tissue by exhaustion asleep. [00:08:00] Right. Supply right tools and camera number of Privacy Rights Center it. We don't choose for you. Science the reasons I've already out there are cells that are now known to be hard to write my partner lines that were isolated in Canada might be why cells grew and those cells may provide some benefit but they don't seem to be repaired and others. [00:08:28] We've really focused on scale while last also known as silent cells of those cells we use are not strictly satellite cells that are going to care. Those cells to get her rights and then obviously the other option is in reality stem cells for doing this why in the end was your transplant but the reality of stem cells might be kind of person who is still Yeah. [00:08:55] So the point one percent sales that we see the most rigid. So there is a you just an understanding of those cells together that's up. This is as a cellular you're a liar as well you're right. Cells is essentially really mirrors here Dr Grant. These are human mind works for us in culture and if you look at some of the options Heidi sleeping right now. [00:09:30] I was told a source for Actually everybody even to eat. You know and a couple have a grand scale muscle that they're willing to use to hear over and over for the marrow of the sleet theory. You know bone marrow depends on where you are good. So really is and whether or not you believe he said it was pretty good lation of cells to be here to. [00:10:00] Particularly for the my I was for my agenda take one was financially. Married right cells. Little foremost hold a will for my party and transplanted into the party. The real the moment this Mike Bloomberg cells is a huge transplant and scarred regions of our you know by their very nature. [00:10:24] There's the environment which they find themselves and they can do. Hard work on people who are good cites slaves tend not to worry my body of one muscle cells in the school or my partner and I you see by using the euro as you know you with the other instances you feel for you guys who really are rights and so you know we certainly would be good options with us again you've been over these reasons use my last minute decision and one of the more scientific reasons to consider using my plan says blue marital rights for homosexuals is that my aunt was normally exist in the region a scar on my soul where there were what supplies will want to play this part. [00:11:25] Well you know for your region and my life on the flights is reduced by about seventy five eighty percent. So the normal course of that was by his instructor region or use for December when the flight was sitting so my parents and they're all supers as we speak. [00:11:45] In addition as you know you could call me like a homer your leg and you're not necessarily going to use these will your leg for hours whereas if you follow the lines by your party you know where you're going to. So the mind has rich Morris even exist we really don't know whether or not given the right cells again for us who may be tracked down the national into the No one described in muscle halfway and to some degree they seem to be able to respond to their hunger to go party at my feet. [00:12:21] Although they don't vote for you. Sites on Facebook who are gaining their data with other stuff. So where are we in terms of real data. What we've really done is we've opened our studies where we create this. So we're there we create right away so we actually read the original Why are you working late. [00:12:53] We're hearing ordering at the same time that takes skill muscle is simply shows a skill piece of skill loss will be pulled up to the privacy. We then expands sells it holds true for a couple weeks we were we're always depending on the numbers that meet prior to transplantation himself we actually do functional study of my party and so that we have a baseline study and work hard and then we transfer cells and actually inject our samples the way anywhere from three to six weeks and you will find that you are your host to see the results of course keep track of cells. [00:13:42] What was the place where I was to believe. So I didn't outline form to talk about briefly is the fact that really this thing here is a way to show and this was done. We're cells in part we now know. We think we do and wish to do so which shows our feeling fosters hasting local state rabbit like our human which we've created or you're likely to be consumers and for his heroes or you know. [00:14:20] In contrast to the British character Jesse and remain where they are you know you can see that even though there's a friend who rules or respects security. It's really good. And that's an important thing to remember just like you know he wouldn't healing process. There's a new engine this is pasted it was in this character. [00:14:42] We already have. There's a lot so I figured the car was. He had some weight and was actually the school so we take advantage of the landscape where it doesn't see us to transplant so this is a new mission it means you've probably seen it was published a number of years ago. [00:15:05] Now why are we telling other below you actually can be a trance your only choice in this case particularly for a friend's place while as you prepare to see again this is a Chinese state and the response where in this region. Do you know this isn't island itself that we were a good to eat for injection ten separate cells three times ten. [00:15:33] Some of the cells in this room it was things you can't really see well in this microgram hopefully see and slightly better thing is that the cells Boria you know what the reactions you can see cells in this way in patients as in this way take these cells are actually coming out like this. [00:15:55] So the cell seems to get some degree avoiding patient base. On the screen as climate sells her data now suggesting that they're pretty much hundred kilometers from your original There would be samples for quiet and skeletal muscle specific transcription you see that we didn't we hire the cells and there's many years in the state. [00:16:24] You just where you go to do this is there some way you see my original state which is never in the normal life already. So my usual was great skeletal muscle. I was really excited and you can see this at the close left the room you would send your leg. [00:16:47] That was pretty impressive or break up this was you know was the only fit for this right now was frozen cereal sections and what we found was that rather than it was lining up as skeletal muscle was forming new fusing or more humiliated prior to that instead new cells was and were connected by what would you give them. [00:17:13] This next life. Right. If you want to do this. He's a good way to give us really these cells and we could not find a more humiliating itself or could you see me like what was interesting here is really shoots through one who is seeing someone who is on you drop my party and has proven Francis and so he might be in prayer and now no one gets these results and stare would seem to see light and that's one of the but it was mostly for example the university. [00:18:00] What you see as sees my eyes are exactly right and see one of my attitudes that he sees I need you to some degree itself for us. You don't know what we are really. So we know that my request where I know you can get seventy five percent of the score filled with these cells. [00:18:33] However we also know and we know that they did this. So what you are resisting the system explosions already. Only going to show you this day to day you so continue to be surrounded by scoff. We are like a life away propagation of the cells the seat is in fact there is some electrical problem but we can't see the pace or the point where for it is the case the cells are good players. [00:19:02] If you don't see where you are getting to the grid grid of the screen you are you personally you face this reality by already. Although we see traction in that region we don't have good evidence like someone sitting there is really interested. All this is whether or not we said we are regional or that something is really data only go where it is actually working to do some modeling for a great test to see if the plant the cells are we need scale was whether or not the way to be more appropriate than a good for us was in contrast Mark Price was there to graft a relatively low that even if we put the horse numbers in the cells and for a few days you can. [00:20:00] More snow was about herself and I'm just having here for a little bit and they seem to go see this to watch it or just it's consistent exposure to the one already in the that's only good news. You couldn't score or you get cells as I said these sites to sites and you know really no get old you know the stuff. [00:20:34] I have for more skill here and the dish and bridge that they keep sells. I hope they stayed at HA last year there's very little murderous from the sales rep or in fact good science. So we get the cells and a prayer. They hang out in Harvard if they don't do anything. [00:21:03] Who cares. So we're going to do well we've got to get these these data or press or second place that you could take him for my party and say this is a cardiac work early. It's like this for the world or you were done on Legion of these or Clark wise news and you Katie is actually done on that region by that. [00:21:31] So this is an aneurism or region of my body and it's not doing any active work itself and we act on the liberal media and that Egypt and wait six weeks we continue seeing all wise and you responded with my very week. You take the stand by. I need to focus on my crystals and my party and there's the distance between those crystals that were ready to cycle and what and who are in power. [00:22:00] Contrast again here is more. We'll plan tend to be a minor what what we see is there and this is around or back to work from negative to positive they become powerful wise and years back when you're young and scientists and one even if we can right relationship with the group working and eyes our second they get painted with very similar to Frank story where they should be homeless or control the ceiling and your relationship after entering my car you take this see exactly what the slow this relation and the ship to the right road we transplant my eyeglasses and we split it with this one where is the chantry you see you can see and hear what we see these. [00:22:57] This is the state actually demonstrated this son who was one of the questions that we always knew I was right. Dissipate was why didn't this happen and initially we thought maybe it was a bit of NATION. Maybe because of putting the cells were we really answer that question we speculate. [00:23:20] Well I think now based on the experience we've done is there is a linear relationship between sun reprieves that we are right and so what we've found is that if we if we measure says shortly. I'm practically in Korea three. It's a brief three and we're is here and he or in your years you see that after ten seven mile last one and crossly. [00:23:50] We send your you in for it. We see you know we hands. Sure we priests. A number of scales to be eight miles away. If you were so small was a new growth system for this region. He used to get worse and where your. We get one is dead or Yes shall we say the usual Madison who returns to the sun. [00:24:30] That's right. He he needs and none could wish guess just as many others. He was showing and the lows are you know you were is you get risen above stuff you keep these here. So because of this one thousand words. I was sharing this fear that someone new to this isn't this is a huge part since our. [00:25:01] You are here and really you know why do we live here or here in this case just once more for the last time and you created and far see again past you will see why in this region already and we injected tend to my cells for weeks I stand and show you a moment of silence so this isn't always the same but it seems like this and this is a over sound image one one post injury and if you look at this region of my body. [00:25:44] You see this is just pieces the rest of us are just being very well this is the region that we are so that we transplanted cells into this part of. And two months later we measured practically you know this is a slightly different view. You can see it really matter of fact the lady because we all live in this region. [00:26:15] So these was something that was good that we are convinced that we can respond right. Really savor this way. There's not a single you know when you're not seeing one practically for the rest of the party and he's saying what we found it is sad and timelessness in here but it's one month we may see through them one by few months to please a man who is really now facts it's just sad to say I was born with rain and you know you don't have to take shelter as you can usually not in the car. [00:27:03] Fortunately I was lucky we need good energy technology was actually visualize and for the fix. It's really to speak. Last evening to sell sell sell for Paris and we also checked in. Archives for it. What we found. First of all this is a scar region for you. We found first of all is that the rest of the letter that my our partner plans do not cool. [00:27:34] Asked for more mileage of cells in the center of the score like my plastic factor disseminated throughout the school and more with me and it is quite a few respects we look at function as maybe not as you would get it in fact right injured or we see again. [00:28:00] A look at your relationship after transplantation was you can prove that it was practically back to our good last we see it continue. We're a society that's simply what we see it. Three and my usual interpretation of the state was well with our eyes it's still the regional heart because our requesting Anjan for a living In fact he just says it was our practice will be what nature being what it is that in her case we could back measure the strain and he's hard so we measure pressure and we constructed pressures ready to give him what we found is as you would expect in a normal life. [00:28:48] Are you as you increase pressure or straining resources and actually risen to start my party and see we had a very stiff region as you would expect we transplanted arguable X. or Y. last we saw essentially the same degree through history and life and what it's trying to be interesting is if we didn't growth factors and give it to you that you have increased where you can see the region we see essentially the same movement. [00:29:21] It's like realty what you introduce patients now place on the estate or. Yes there can be something living in the region the school or the whatever else schools or living cells is actually better for relaxation of the party and have a separate from the major It's there but it takes a practical cell that it says so. [00:29:51] You know this is one reason why I didn't shoot any boy David you know that includes globally as well as regionally. And I concentrated primarily on rabbit. But very very much. It was for a show. I personally track and eat and also inhale others from other lands for years independent of any form of model initially this really isn't right to simply function just zero tolerance for the basic one zero recently moment and the most recent to this is why we really are really like Asian girls. [00:30:31] We still see the same where you really can't leave the house and it appears fairly good kind of a map and a sense of where we use on my own free will. Over say we still see improvements practically last week. That's so life is critical. We don't see my roots with some lights I think the jury is still out on whether you're right. [00:31:03] Cells within hearing you this and the story right now we can hold this seat and yet come up here when you're doing it the number of days. You know the bottom line question is then what is is said and good really striking and that's all that none of us to see with geniuses in these parts and he's all right you're your party and I think that's actually this is still surrounded by support Senator Daschle insulated from the surrounding party workers and that most of it rightfully seat is secondary and France Russia. [00:32:00] Absolutely right. And we've started actually making measurements now and rightfully You know look synchronous there is a second millisecond to let practically see Egypt versus the forty we're trying to do so much more detail than that to see if there's a life. What it's like so how does it work. [00:32:33] Does it increase contraction because we believe that my rights do cause me nicely and we're pleased to cause if we can to get to the stuff that's OUR was telling data that it actually is practically versus a change very hard for a number of it's also possible when it came it to them already. [00:33:00] That is like putting cells in the time process. We really are. If you change the rules grass on the surrounding or so that if you don't have a clue you are these places around the regions you get less when my back. Lets you know the neighborhoods and just where possible you don't really talk about the laws of the cells or maybe just littered with the growth factors or genes like that you're right here while things that it's important to remember is no matter how much warning. [00:33:38] You we're not going to have a group published. We know that our last week. Actually you know a little higher last minute or so is here. It will also do this in fact that's one of the reasons you sell is because this heat cycle. Getting a hold of factors on our side for the leaders here really is on the story. [00:34:13] But what can we generate in the end huge issue. I want to very briefly should yours. I wish data were actually pretty small to deliver an agenda to the skeletal muscle group group was alive and that we should remember it now we initially thought it was only our recent years and here patiently to do with good vision and with these kids in our school i problem was very similar and this week and he was in the region are you sure we do the right thing or is listed missing that spirit. [00:35:07] I will go and see friction is backed up and in fact you can deliver on a lower one is he likely wrote those fires or better have a long period of time he might in fact it will be on the side effects and one way to do next is we're moving your protein you get something. [00:35:29] This is a character who gets the credit for that and we're dealing with our cycles and saw increase every density in meat and some improvement in practically all of the state police and so instead we decided to take advantage of the fact that the grower cells in the dish. [00:35:51] Although you're Greek A and we could in fact check the cells blue. Better than ours make him. And not have to do that. Mars. Will say the much for you to lose cells and keep it here. So initially we did experiments for it ready to display as muscle biopsy expanded the cells in the same way and we created a time when the skin can actually this is like when the skin fusion and overstressed and injected the signals back and that region. [00:36:34] And what we see here is this is one of the songs for us and so we all sections of the skeletons that we see the skull. You see and this is a white Gram who can muscle Farber's seat or the periphery of the muscle car or bundle and you see that all of the rest of the way who knew it was really moving in the right really. [00:37:04] This was a woman who was actually working for the muscles you expect you are going to hear what was really cool is when you look at where it gets what we were able to show is it in her control and see if you measure the camp or density as the Senate is what we actually risky here we slow down twenty five percent of the sham free. [00:37:33] We freeze every day. As for we used him T.V. and the Carters this is where he changes information secondary hires and then we deliver venture partners who can actually see the sun in present carry on race and then we do it for my class. Just plan higher what we do. [00:37:57] Maybe someone will manage to have control. Tamerlan was saying. Actually we saw actually a greater degree of risk where you can see that he did he would be better for us we were all my last rights expressing You can see that we care about seventy five percent of all and again to show you care. [00:38:22] Sure looks like this is a hundred wounded. He says untreated. And this is activity that the violence spreads you can see in the city so we can we never lose all interest in these so we're convinced that we can use these cells Luci rather this way over the next. [00:38:51] So is my quest for a good work patience USAID they are in carry on and he should this is actually the USA Today. That's what I wish there were the fringe groups where he's like OK I'm OK with it. We're going to destroy it. Right. They actually get in their clinical trial. [00:39:27] Yes take patients we're going to see or hear your report castrated. And transplant their prices or their life. As frail and the reason they said would not be retested. And there were all. And then actually he was practically viability that Legion was forty or so. See in patients we know we really want and see if I so the British for it then I want to date or surgical results for my own or bypass graft and say look are you my eyes they were seated six patients. [00:40:20] There's been one to look good to so who are going to patient and has it occurred in four minutes we say that's secondary. So there really is in fact the size of the CT stare. There's been a three to ten month and if you look at the left that's critical reaction right. [00:40:47] Preoperatively somebody who gives more than about thirty percent and patients. So this is really a safety trial says that there is only one death and it appears the only way to cellular so that five patients cells to live to do five months. We are without and yet on the follow his mind and we really can't say that there is he would tell us he sells me as and just like the solution and message a response are going to pull for X. here and rather than him. [00:41:43] It's five patients or I would say I understand it but he said it was reported by Dr was this is a five patients are doing good. Right here you patients have to be eighteen years of age at seventy five years of age and to have it in for at least four weeks ago and a generation or greater than what you would require you see and you told us this is going to be a single three right after the break. [00:42:19] So there are three in the absence of any under three you have to have a regional war that has created five millimeters in the region where you can inject cells you really can't afford the rate and yet again and that's right. One patient has received cells and the patient is doing well. [00:42:42] Two months and my understanding is it's two patients who received cells in the next week or so and so that's right. He's following the right. We're staying in Europe. We will in the U.S. there's a face one group prior to two little mild lands patients who see exactly what resistant I says my diary and also his hand corner of my past where again both of these today and other treatments being done. [00:43:16] Are you know the advantage would be OK for my opinion in that area is it so easy patients who are less and will be encouraged to take the time. Are you actually see you. The cells there and fire expects to see you see face what was already vascular pace in the secondary but I wouldn't change it now for me. [00:43:54] Really I just think that will do what it will. Crowd size really is good because you really are way better makes more sense patients just have it right. There's less one bit. And so you're more likely to get a positive outcome for Haitians who have no option but are there for this really does have a negative out or is it you can't really sell those patients who just have it without proving that it's safe. [00:44:34] They really setting themselves up and actually I've written here. We're jumping over the same people for a second here you have seen data but how can you really say there's debate you will go and bring this up. Even if you do read it. Groups that are you know just solutions. [00:44:57] All of which one can forward. Here's one subset of patients say all the various forms that you write. It's just like they range from page to page so where do we think we're going to get an issue in Europe we expect there to be a safety activist right here it is going to be a surgical sample three hundred cells not heritage healthcare just a little or yourself you know the fringe group is going for this you know several companies so there's also been no marriage right out of the bone or rights from our own initiative in Singapore and brought to me that's an investigator sponsored right that we really didn't expect this year which we replied. [00:45:53] OK I'm out here. I'm rose from the sofa leak Section two grants so. He and i Pads will be true but we respect and ask who wrote fire again it was an investigator sponsored for its underwear and expects civil liberties to get files. If you in the US. [00:46:23] Expect Iran to move it. Phase two trials. We know that your investigators through trials better be getting and unfortunately everyone seems to think that this is a mighty Roselle and you hand it he my life is good that you wrote is going to work for these girls and I'm here to tell you after ten years of doing this and I said I was not to sell we get this one hundred percent of it back from ten years of experience and every time we have a new surgery fellow at the last person in learning and everything changes. [00:47:02] So I'm afraid you may see some negative. It will we see on the side of his field and we know that there's a button or stem cell saying keep trying. There's fire as it is getting and he says well you can't take anything out of home take home the message that if you do this right we're going to do this deal. [00:47:23] We're going to set you back five or six years just watching your he was tired. See you eat which is which as if there is no doubt. I believe you go through this. Let me just cite it to go forward with multiple patient populations. We're going to do with a surgical bookkeeping history and Additionally although we're focusing on higher class what we've said quote I had one astronaut. [00:48:00] The answer to your hands that we want to be answer is usually we know the cells say why this is such a big deal. Well it's a big deal. There's a huge out there. Yes this is from a document all the skaters guide to the hard spoke with investors like to the part that was published last year you can see that Carney actually to regeneration really didn't even get people to listen to this three years ago is now to be viewed as either largest market five point three billion have a seven point three billion dollars market in the US it's still going to really go forward. [00:49:14] I really would like to give credit to the people who actually did this work. I collaborated for a number of years with flour is a good idea for as a service and probably will buy near the ability to measure region are you going to her surgery fellows who work with me as well as you're a lawyer or young and she was Raiders for the I'll just write hands and it's. [00:49:44] Russell and he let Michael that really do work that. Thank you. My floors. What was the market. There were a hundred mesh so it was very very low. I would say walks very well I think the only way to answer that is to do small experiments and that's very expensive but I think that's actually the same situation as well we really need to do this is something that's going to work for you for such a good few years and you're going to be able to deliver and there was a good friend of my friend Lisa rather than the cells and still zero point zero one of the things that is really kind of interesting is that number of change a really really really smiles. [00:51:28] This year it's practically and then they harvest of cells cells and I don't know why you say we don't know the cells actually the right one go away. Why do I think the cells are good ever come and who are your sites. I think that depends on whether he will use them in the trial. [00:51:57] If we wish to forward. On the British way be for you. They're going to criticize you then. When they have to go. Yes but only right here since we're doing so over experiments now that right understanding of the changes that are and what we found is if we can over these really really remarkable stimulate say I believe that this is this these changes are super musicians learned and changes and one woman is not going to get this back. [00:52:36] So by doing some polka for experiments and some like lation experiments we're getting a good show. We can get her your plants push factors on these cells on your roof and then we take fish ear off and so we get back. So it's livelihood and you know my mind for six years we've tried expecting earlier. [00:53:13] That's for sure. Factors and the cells and the for life which are yet when we just really think he does it much better. We do and even and I should say that Michael what are these sites like for you. But you know where you are right that is the cell story expressing right here and also I should say I didn't say it was you chosen to do right. [00:54:22] So I was once in a scam that was I think that scandal was going to continue just like going to Moscow. It was oxidative Moscow and then you're stuck part which is you know it's a little slow and I think by choosing so I was in the accident it did it can you know we there's itself that already is grounds for a license to change for example and express some of the same radical groups that have been reports and also express. [00:54:51] Where is it yes and the quietly. If it spreads to save her life. I'm speculating. We know that that as he was foreign troops and we go from ten three to one on these in these parts but we don't know yet is whether or not and where cells is it you might say we just started barely measuring in peace when everything started really interesting and her Steve and his wife and I were express the ease and it's been a great source of. [00:56:00] It's really really stupid really we know very well the Matrix and that's a group that's Haitian but that's just and something resources something you hear about this and what we understand part is just fine. It was really looking like questions right here right. Why are there. So yeah there are you're sure of it. [00:56:50] The question was we were under something which you yourself are really wired to take you wrote this respect or especially it was thinking about you as patients because it's a whole lot easier if you get fired last and and not have to do a lot of that. So which gets in bone marrow to your whole life was self defense lest you go wrong on the other hand if you can't write a long term solution. [00:57:25] Now do something this size or do something for yourself right here in our farming about the fact that it was an egg cells are obviously the mind young which he or she may be for having the shell rather Michael reproducible bachelor nice criteria for funky product on the other hand a new hand and where we're you know suppressing reagents to people who are already very sick and already have compromised renal function as they have heard them. [00:58:00] And then you're looking at a significant downside so you've chosen to digitally go watch all of this White House and still working with the ministers of cells and others in Nations to see if they make sense.